Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1923224..1923814 Replicon chromosome
Accession NZ_CP099903
Organism Escherichia albertii strain 133_1_GWG_A

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag NIY95_RS09180 Protein ID WP_059225520.1
Coordinates 1923482..1923814 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag NIY95_RS09175 Protein ID WP_059225519.1
Coordinates 1923224..1923481 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIY95_RS09165 (1922204) 1922204..1922674 + 471 WP_059225518.1 hypothetical protein -
NIY95_RS09170 (1922671) 1922671..1922876 + 206 Protein_1789 helix-turn-helix domain-containing protein -
NIY95_RS09175 (1923224) 1923224..1923481 + 258 WP_059225519.1 hypothetical protein Antitoxin
NIY95_RS09180 (1923482) 1923482..1923814 + 333 WP_059225520.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NIY95_RS09185 (1923927) 1923927..1924304 + 378 WP_161537949.1 hypothetical protein -
NIY95_RS09190 (1924622) 1924622..1925506 + 885 WP_059225521.1 integrase domain-containing protein -
NIY95_RS09195 (1925602) 1925602..1925889 - 288 WP_059225522.1 hypothetical protein -
NIY95_RS09200 (1926848) 1926848..1928110 - 1263 WP_059225524.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-85)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11777.59 Da        Isoelectric Point: 8.0291

>T249844 WP_059225520.1 NZ_CP099903:1923482-1923814 [Escherichia albertii]
MDRGEIWLVSLDPIAGHEQSGKRPVLIVSPASFNEVTRLPVIVPVTSGGQFARSAGFAVSLEGAGTKTTGIIRCDQPRTI
DMGARNGKRLERIPDGIINEVLARLETILA

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9314.80 Da        Isoelectric Point: 4.4488

>AT249844 WP_059225519.1 NZ_CP099903:1923224-1923481 [Escherichia albertii]
MYTTRLKKVGGSVMLAVPPAVLKTLALLPDSEVGVTIDNGCLIIEPQKRPRYSLAELLAQCDPHEEISDEEREWIDAPAA
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References