Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 297144..297944 Replicon chromosome
Accession NZ_CP099895
Organism Escherichia albertii strain 153_2_TBG_A

Toxin (Protein)


Gene name ataT Uniprot ID A0A8H9C5V7
Locus tag NIZ14_RS01375 Protein ID WP_000342455.1
Coordinates 297417..297944 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID B1EHP0
Locus tag NIZ14_RS01370 Protein ID WP_001277106.1
Coordinates 297144..297410 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ14_RS01350 (292740) 292740..293798 + 1059 WP_001042000.1 permease-like cell division protein FtsX -
NIZ14_RS01355 (294043) 294043..294897 + 855 WP_000130217.1 RNA polymerase sigma factor RpoH -
NIZ14_RS01360 (295094) 295094..295603 + 510 WP_059235675.1 hypothetical protein -
NIZ14_RS01365 (295891) 295891..296994 + 1104 WP_010319184.1 branched chain amino acid ABC transporter substrate-binding protein LivJ -
NIZ14_RS01370 (297144) 297144..297410 + 267 WP_001277106.1 type II toxin-antitoxin system antitoxin AtaR Antitoxin
NIZ14_RS01375 (297417) 297417..297944 + 528 WP_000342455.1 type II toxin-antitoxin system toxin acetyltransferase AtaT Toxin
NIZ14_RS01380 (297941) 297941..298324 - 384 WP_059235673.1 aspartate 1-decarboxylase autocleavage activator PanM -
NIZ14_RS01385 (298748) 298748..299857 + 1110 WP_256875830.1 high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK -
NIZ14_RS01390 (299905) 299905..300831 + 927 WP_001295111.1 high-affinity branched-chain amino acid ABC transporter permease LivH -
NIZ14_RS01395 (300828) 300828..302105 + 1278 WP_044709902.1 branched chain amino acid ABC transporter permease LivM -
NIZ14_RS01400 (302102) 302102..302869 + 768 WP_044709901.1 high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-150)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19607.47 Da        Isoelectric Point: 6.6343

>T249791 WP_000342455.1 NZ_CP099895:297417-297944 [Escherichia albertii]
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCSNTPERQVLGYYTLSGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYQSLGFIPLVGENENAL
FFPTKSIELLFTQSD

Download         Length: 528 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9942.37 Da        Isoelectric Point: 10.0863

>AT249791 WP_001277106.1 NZ_CP099895:297144-297410 [Escherichia albertii]
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQHRRMILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z8E004

References