Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2629806..2630584 Replicon chromosome
Accession NC_014722
Organism Burkholderia rhizoxinica HKI 454

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag RBRH_RS11640 Protein ID WP_041753901.1
Coordinates 2630093..2630584 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag RBRH_RS11635 Protein ID WP_041753900.1
Coordinates 2629806..2630096 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RBRH_RS11615 2626072..2626938 + 867 WP_013436496.1 SDR family oxidoreductase -
RBRH_RS11620 2626973..2627476 - 504 WP_013436497.1 DUF72 domain-containing protein -
RBRH_RS11625 2627608..2628117 - 510 WP_041753898.1 hemerythrin domain-containing protein -
RBRH_RS11630 2628484..2629002 + 519 WP_041753899.1 hypothetical protein -
RBRH_RS11635 2629806..2630096 + 291 WP_041753900.1 DUF1778 domain-containing protein Antitoxin
RBRH_RS11640 2630093..2630584 + 492 WP_041753901.1 GNAT family N-acetyltransferase Toxin
RBRH_RS11650 2631082..2631483 - 402 WP_157864497.1 c-type cytochrome -
RBRH_RS11655 2631492..2632277 - 786 WP_041753902.1 BON domain-containing protein -
RBRH_RS11660 2632300..2632887 - 588 WP_041753903.1 SIS domain-containing protein -
RBRH_RS11665 2632920..2633420 - 501 WP_013436505.1 YraN family protein -
RBRH_RS11670 2633501..2634328 + 828 WP_173362436.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
RBRH_RS11675 2634390..2635031 - 642 WP_041753904.1 septal ring lytic transglycosylase RlpA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(85-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17864.59 Da        Isoelectric Point: 8.5219

>T24979 WP_041753901.1 NC_014722:2630093-2630584 [Mycetohabitans rhizoxinica HKI 454]
MTIEAPEPLASHHELDAFTSGVESLDQWLKRRALKNQTTGASRTFVACAERRVRAYYALASSAVTVDAAPGRFRRNMPDP
IPVVVLGRLAVDQSWHGRGLGRALVKDACLRVIQAADTIGIRGMLVHALSDETRAFYERIGFEGSQLDPMMLMVTLADLK
ASV

Download         Length: 492 bp

>T24979 NC_014722:2630093-2630584 [Mycetohabitans rhizoxinica HKI 454]
ATGACGATTGAAGCCCCCGAACCGCTTGCATCCCATCATGAGCTGGATGCATTCACGTCGGGCGTCGAAAGTCTGGACCA
GTGGCTAAAGCGTCGTGCGCTGAAAAATCAGACCACGGGTGCTTCGCGCACCTTCGTCGCTTGTGCCGAGCGTCGGGTGC
GGGCGTACTACGCGTTGGCATCGAGCGCCGTCACGGTAGATGCGGCCCCTGGCCGCTTTCGACGCAATATGCCAGATCCG
ATACCGGTTGTGGTTCTGGGGCGGTTGGCCGTAGACCAGTCGTGGCATGGTAGAGGGCTCGGGCGCGCTTTGGTCAAGGA
TGCTTGCCTGCGCGTGATCCAGGCGGCCGACACGATCGGTATTCGGGGCATGTTGGTGCATGCACTCTCTGACGAAACTC
GGGCCTTTTATGAGCGGATCGGTTTCGAAGGATCGCAGCTTGATCCGATGATGCTTATGGTAACGCTTGCCGACTTAAAA
GCTAGCGTGTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10604.18 Da        Isoelectric Point: 10.4666

>AT24979 WP_041753900.1 NC_014722:2629806-2630096 [Mycetohabitans rhizoxinica HKI 454]
MTAANAQPTKRDTLNIRIKPEERNLIDRAAKVRGKNRTDFVLEAARTAAEEALLDQAIITASPKAYAAFVVRLDLPPQPN
EALRKTLQAPAPWDKA

Download         Length: 291 bp

>AT24979 NC_014722:2629806-2630096 [Mycetohabitans rhizoxinica HKI 454]
ATGACCGCCGCAAACGCACAACCCACGAAGCGCGACACGCTCAATATCCGGATCAAGCCTGAAGAGCGGAATCTGATCGA
CCGCGCCGCAAAGGTCCGCGGGAAGAATCGAACGGATTTCGTGCTCGAGGCTGCTCGAACGGCAGCGGAAGAGGCCTTGC
TTGACCAAGCCATCATCACGGCTTCACCGAAGGCTTACGCGGCCTTTGTAGTGCGTTTGGATCTGCCGCCGCAACCCAAC
GAGGCTCTGCGCAAAACGCTACAGGCGCCAGCGCCGTGGGACAAGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References