Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 1196552..1197147 Replicon chromosome
Accession NZ_CP099890
Organism Escherichia albertii strain 205_2_TBG_B

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag NIZ17_RS06035 Protein ID WP_059255551.1
Coordinates 1196552..1196902 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag NIZ17_RS06040 Protein ID WP_059255553.1
Coordinates 1196896..1197147 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ17_RS06015 (1192158) 1192158..1192979 + 822 WP_256880538.1 PfkB family carbohydrate kinase -
NIZ17_RS06020 (1193139) 1193139..1194521 + 1383 WP_256880539.1 sugar porter family MFS transporter -
NIZ17_RS06025 (1194607) 1194607..1195107 + 501 WP_059255546.1 D-ribose pyranase -
NIZ17_RS06030 (1195120) 1195120..1196499 + 1380 WP_085455823.1 sugar porter family MFS transporter -
NIZ17_RS06035 (1196552) 1196552..1196902 - 351 WP_059255551.1 type II toxin-antitoxin system ChpB family toxin Toxin
NIZ17_RS06040 (1196896) 1196896..1197147 - 252 WP_059255553.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NIZ17_RS06045 (1197356) 1197356..1197700 - 345 WP_001219163.1 gamma-glutamylcyclotransferase -
NIZ17_RS06050 (1197703) 1197703..1201482 - 3780 WP_256880540.1 autotransporter assembly complex protein TamB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12631.65 Da        Isoelectric Point: 5.1420

>T249750 WP_059255551.1 NZ_CP099890:c1196902-1196552 [Escherichia albertii]
MVKRSEFERGDIMLVGFDPASGHEQRGAGRPVLVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLRCEEGDVCGVVVV
NQVRMMDLNARQAKRIGLACDEVVEEVLLRLQAVVE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9237.69 Da        Isoelectric Point: 4.9431

>AT249750 WP_059255553.1 NZ_CP099890:c1197147-1196896 [Escherichia albertii]
MRITIKKWGNSAGMVIPNIVMKGLKLQPGQSLEAQVRNNQLILTPVSKRYSLDELLAQCDMNAPELSEQDVWGTLSPAGD
EIW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References