Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 2468271..2468866 Replicon chromosome
Accession NZ_CP099886
Organism Escherichia albertii strain 222_1_EW_B

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag NIZ19_RS12015 Protein ID WP_059255551.1
Coordinates 2468516..2468866 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag NIZ19_RS12010 Protein ID WP_059255553.1
Coordinates 2468271..2468522 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NIZ19_RS12000 (2463936) 2463936..2467715 + 3780 WP_256876889.1 autotransporter assembly complex protein TamB -
NIZ19_RS12005 (2467718) 2467718..2468062 + 345 WP_001219163.1 gamma-glutamylcyclotransferase -
NIZ19_RS12010 (2468271) 2468271..2468522 + 252 WP_059255553.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NIZ19_RS12015 (2468516) 2468516..2468866 + 351 WP_059255551.1 type II toxin-antitoxin system ChpB family toxin Toxin
NIZ19_RS12020 (2468919) 2468919..2470298 - 1380 WP_256876890.1 sugar porter family MFS transporter -
NIZ19_RS12025 (2470311) 2470311..2470811 - 501 WP_256876891.1 D-ribose pyranase -
NIZ19_RS12030 (2470897) 2470897..2472279 - 1383 WP_256876892.1 sugar porter family MFS transporter -
NIZ19_RS12035 (2472293) 2472293..2473261 - 969 WP_256876893.1 PfkB family carbohydrate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12631.65 Da        Isoelectric Point: 5.1420

>T249697 WP_059255551.1 NZ_CP099886:2468516-2468866 [Escherichia albertii]
MVKRSEFERGDIMLVGFDPASGHEQRGAGRPVLVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLRCEEGDVCGVVVV
NQVRMMDLNARQAKRIGLACDEVVEEVLLRLQAVVE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9237.69 Da        Isoelectric Point: 4.9431

>AT249697 WP_059255553.1 NZ_CP099886:2468271-2468522 [Escherichia albertii]
MRITIKKWGNSAGMVIPNIVMKGLKLQPGQSLEAQVRNNQLILTPVSKRYSLDELLAQCDMNAPELSEQDVWGTLSPAGD
EIW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References