Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 5484152..5484812 Replicon chromosome
Accession NZ_CP099837
Organism Nocardiopsis exhalans strain JCM11759T

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NE857_RS24215 Protein ID WP_254417792.1
Coordinates 5484408..5484812 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NE857_RS24210 Protein ID WP_254417791.1
Coordinates 5484152..5484415 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE857_RS24200 (NE857_24200) 5480785..5482863 + 2079 WP_254422080.1 biotin carboxylase N-terminal domain-containing protein -
NE857_RS24205 (NE857_24205) 5482860..5484017 + 1158 WP_254417790.1 acyl-CoA dehydrogenase family protein -
NE857_RS24210 (NE857_24210) 5484152..5484415 + 264 WP_254417791.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NE857_RS24215 (NE857_24215) 5484408..5484812 + 405 WP_254417792.1 type II toxin-antitoxin system VapC family toxin Toxin
NE857_RS24220 (NE857_24220) 5485106..5486050 + 945 WP_254417793.1 serine/threonine-protein kinase -
NE857_RS24225 (NE857_24225) 5486406..5487095 + 690 WP_254417794.1 hypothetical protein -
NE857_RS24230 (NE857_24230) 5487251..5487409 + 159 WP_184365480.1 hypothetical protein -
NE857_RS24235 (NE857_24235) 5487506..5489482 - 1977 WP_017581535.1 threonine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-61)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14297.56 Da        Isoelectric Point: 4.8889

>T249528 WP_254417792.1 NZ_CP099837:5484408-5484812 [Nocardiopsis exhalans]
MPESHASGVLATCAFIDLPVLDPAVLPDFPEITSVTMAELHQGIAMAKEPVARAARTERLQAAAVDFVPLPFDGEAAARY
GTLVALTIAENRSPKPRRMDLMIASIASVHALPLHTRNAEDFKGLESALEVIAI

Download         Length: 405 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9973.05 Da        Isoelectric Point: 4.9737

>AT249528 WP_254417791.1 NZ_CP099837:5484152-5484415 [Nocardiopsis exhalans]
MKTITQREFRNKAAAVMDAVEAGETFHVTRNGVEVAEVRPIARRRKLSAQELVERHQRLPRVDHAEMRDEAEDFFGDEDL
GGEDEHA

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References