Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 786478..787135 Replicon chromosome
Accession NZ_CP099834
Organism Klebsiella quasipneumoniae strain Y7-3

Toxin (Protein)


Gene name cptA Uniprot ID A0A2N4VX63
Locus tag NDO72_RS03905 Protein ID WP_023290968.1
Coordinates 786725..787135 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W8UQ37
Locus tag NDO72_RS03900 Protein ID WP_002916312.1
Coordinates 786478..786744 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NDO72_RS03875 (781628) 781628..783061 - 1434 WP_023290972.1 6-phospho-beta-glucosidase BglA -
NDO72_RS03880 (783180) 783180..783908 - 729 WP_032454033.1 MurR/RpiR family transcriptional regulator -
NDO72_RS03885 (783959) 783959..784270 + 312 WP_023290970.1 N(4)-acetylcytidine aminohydrolase -
NDO72_RS03890 (784434) 784434..785093 + 660 WP_008806429.1 hemolysin III family protein -
NDO72_RS03895 (785249) 785249..786232 - 984 WP_060590308.1 tRNA-modifying protein YgfZ -
NDO72_RS03900 (786478) 786478..786744 + 267 WP_002916312.1 FAD assembly factor SdhE Antitoxin
NDO72_RS03905 (786725) 786725..787135 + 411 WP_023290968.1 protein YgfX Toxin
NDO72_RS03910 (787143) 787143..787664 - 522 WP_004205324.1 flavodoxin FldB -
NDO72_RS03915 (787765) 787765..788661 + 897 WP_044524682.1 site-specific tyrosine recombinase XerD -
NDO72_RS03920 (788684) 788684..789397 + 714 WP_002916301.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NDO72_RS03925 (789403) 789403..791136 + 1734 WP_253230893.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16075.89 Da        Isoelectric Point: 11.4778

>T249512 WP_023290968.1 NZ_CP099834:786725-787135 [Klebsiella quasipneumoniae]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
EWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDPGEWRDLRRLVLQKPAQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10480.98 Da        Isoelectric Point: 5.1116

>AT249512 WP_002916312.1 NZ_CP099834:786478-786744 [Klebsiella quasipneumoniae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKQLFIRLLENDDPDLFNWLMNHGKPADAELQRMVTLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N4VX63

Antitoxin

Source ID Structure
AlphaFold DB A0A0H3GY41

References