Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1968941..1969859 Replicon chromosome
Accession NZ_CP099815
Organism Yersinia ruckeri strain NVI-11050

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LNQ40_RS09050 Protein ID WP_038242633.1
Coordinates 1969401..1969859 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag LNQ40_RS09045 Protein ID WP_038242631.1
Coordinates 1968941..1969387 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ40_RS09025 (LNQ40_009015) 1964639..1965343 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
LNQ40_RS09030 (LNQ40_009020) 1965354..1966328 - 975 WP_071666721.1 L-Ala-D/L-Glu epimerase -
LNQ40_RS09035 (LNQ40_009025) 1966478..1966981 + 504 WP_004717547.1 thiol peroxidase -
LNQ40_RS09040 (LNQ40_009030) 1967016..1968623 - 1608 WP_038251390.1 transcriptional regulator TyrR -
LNQ40_RS09045 (LNQ40_009035) 1968941..1969387 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
LNQ40_RS09050 (LNQ40_009040) 1969401..1969859 + 459 WP_038242633.1 RES domain-containing protein Toxin
LNQ40_RS09055 (LNQ40_009045) 1969863..1970921 - 1059 WP_071666720.1 YcjF family protein -
LNQ40_RS09060 (LNQ40_009050) 1970918..1972315 - 1398 WP_004717556.1 YcjX family protein -
LNQ40_RS09065 (LNQ40_009055) 1972296..1972538 - 243 WP_087931058.1 phage shock protein PspD -
LNQ40_RS09070 (LNQ40_009060) 1972602..1972961 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
LNQ40_RS09075 (LNQ40_009065) 1972961..1973188 - 228 WP_038242637.1 envelope stress response membrane protein PspB -
LNQ40_RS09080 (LNQ40_009070) 1973272..1973937 - 666 WP_004717561.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17072.55 Da        Isoelectric Point: 6.6384

>T249506 WP_038242633.1 NZ_CP099815:1969401-1969859 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT249506 WP_038242631.1 NZ_CP099815:1968941-1969387 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References