Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 938319..938942 Replicon chromosome
Accession NZ_CP099813
Organism Yersinia ruckeri strain NVI-492

Toxin (Protein)


Gene name Hha Uniprot ID A0A085U5C4
Locus tag LNQ24_RS04135 Protein ID WP_038243726.1
Coordinates 938319..938522 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A085U5C5
Locus tag LNQ24_RS04140 Protein ID WP_004718732.1
Coordinates 938574..938942 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ24_RS04110 (LNQ24_004115) 934174..934512 + 339 WP_007886947.1 P-II family nitrogen regulator -
LNQ24_RS04115 (LNQ24_004120) 934551..935840 + 1290 WP_004718723.1 ammonium transporter AmtB -
LNQ24_RS04120 (LNQ24_004125) 935955..936818 - 864 WP_004718726.1 acyl-CoA thioesterase II -
LNQ24_RS04125 (LNQ24_004130) 937196..937510 - 315 WP_248577445.1 MGMT family protein -
LNQ24_RS04135 (LNQ24_004140) 938319..938522 - 204 WP_038243726.1 expression modulating protein YmoA Toxin
LNQ24_RS04140 (LNQ24_004145) 938574..938942 - 369 WP_004718732.1 Hha toxicity modulator TomB Antitoxin
LNQ24_RS04145 (LNQ24_004150) 939991..940152 + 162 WP_004718735.1 hypothetical protein -
LNQ24_RS04150 (LNQ24_004155) 940271..940414 - 144 WP_004718738.1 type B 50S ribosomal protein L36 -
LNQ24_RS04155 (LNQ24_004160) 940434..940688 - 255 WP_038243728.1 type B 50S ribosomal protein L31 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-117)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8037.27 Da        Isoelectric Point: 6.4573

>T249494 WP_038243726.1 NZ_CP099813:c938522-938319 [Yersinia ruckeri]
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPATVWQHVK

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14277.08 Da        Isoelectric Point: 4.4225

>AT249494 WP_004718732.1 NZ_CP099813:c938942-938574 [Yersinia ruckeri]
MDEYSPKRHDIAQLKFLCENLYDEGIATLGDSHHGWVNDPTSAVNLQLNDLIEHIASFVMSFKIKYADEIDLCELVEEYL
DDTYTLFSSYGINDPDLRRWQKTKDRLFRLFSGEYLCALMKN

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A085U5C4

Antitoxin

Source ID Structure
AlphaFold DB A0A085U5C5

References