Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 3152694..3153416 Replicon chromosome
Accession NZ_CP099811
Organism Yersinia ruckeri strain NVI-9681

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag LNQ37_RS14705 Protein ID WP_234054819.1
Coordinates 3152694..3153014 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LNQ37_RS14710 Protein ID WP_234055013.1
Coordinates 3153081..3153416 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ37_RS14690 (LNQ37_014680) 3149489..3151330 + 1842 WP_004723328.1 RNA polymerase sigma factor RpoD -
LNQ37_RS14700 (LNQ37_014690) 3151747..3152580 - 834 WP_234054818.1 DUF4942 domain-containing protein -
LNQ37_RS14705 (LNQ37_014695) 3152694..3153014 - 321 WP_234054819.1 TA system toxin CbtA family protein Toxin
LNQ37_RS14710 (LNQ37_014700) 3153081..3153416 - 336 WP_234055013.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LNQ37_RS14715 (LNQ37_014705) 3153430..3153909 - 480 WP_234054820.1 DNA repair protein RadC -
LNQ37_RS14720 (LNQ37_014710) 3154610..3155428 + 819 WP_234054821.1 HNH endonuclease signature motif containing protein -
LNQ37_RS14725 (LNQ37_014715) 3155494..3155934 + 441 WP_234054822.1 hypothetical protein -
LNQ37_RS14730 (LNQ37_014720) 3156129..3157279 + 1151 WP_248578295.1 IS3 family transposase -
LNQ37_RS14735 (LNQ37_014725) 3157297..3157731 - 435 Protein_2857 Arm DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(7-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12071.61 Da        Isoelectric Point: 5.0486

>T249492 WP_234054819.1 NZ_CP099811:c3153014-3152694 [Yersinia ruckeri]
MQTTTVPATLPVSSRQSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDASIEEHIEAGITLADAVNFLVERYELVRTDRKGF
TWQEQTPFLTATDILRAKRATGLMNT

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12590.28 Da        Isoelectric Point: 6.3163

>AT249492 WP_234055013.1 NZ_CP099811:c3153416-3153081 [Yersinia ruckeri]
MNNDDTQTWGLKRDITPCFGARLVQEGHRLHFLADRAEFNGSFSEMQARVLDKAFPHFVAHMELMLLSGELNPRYSHCVT
LYRNGLTCEADTLGSYGYVYIAIYPSNLVTA

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References