Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3002608..3003277 Replicon chromosome
Accession NZ_CP099811
Organism Yersinia ruckeri strain NVI-9681

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag LNQ37_RS14025 Protein ID WP_038241020.1
Coordinates 3002608..3003030 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LNQ37_RS14030 Protein ID WP_004719196.1
Coordinates 3003011..3003277 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ37_RS14005 (LNQ37_013995) 2998447..3000180 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
LNQ37_RS14010 (LNQ37_014000) 3000187..3000903 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LNQ37_RS14015 (LNQ37_014005) 3000935..3001834 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
LNQ37_RS14020 (LNQ37_014010) 3001942..3002460 + 519 WP_038241022.1 flavodoxin FldB -
LNQ37_RS14025 (LNQ37_014015) 3002608..3003030 - 423 WP_038241020.1 protein YgfX Toxin
LNQ37_RS14030 (LNQ37_014020) 3003011..3003277 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
LNQ37_RS14035 (LNQ37_014025) 3003571..3004563 + 993 WP_038241018.1 tRNA-modifying protein YgfZ -
LNQ37_RS14040 (LNQ37_014030) 3004702..3005367 - 666 WP_175537887.1 hemolysin III family protein -
LNQ37_RS14045 (LNQ37_014035) 3005684..3005940 + 257 Protein_2722 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T249491 WP_038241020.1 NZ_CP099811:c3003030-3002608 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT249491 WP_004719196.1 NZ_CP099811:c3003277-3003011 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References