Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1864412..1865330 Replicon chromosome
Accession NZ_CP099811
Organism Yersinia ruckeri strain NVI-9681

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LNQ37_RS08325 Protein ID WP_038242633.1
Coordinates 1864872..1865330 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag LNQ37_RS08320 Protein ID WP_038242631.1
Coordinates 1864412..1864858 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ37_RS08300 (LNQ37_008295) 1860110..1860814 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
LNQ37_RS08305 (LNQ37_008300) 1860825..1861799 - 975 WP_038275966.1 L-Ala-D/L-Glu epimerase -
LNQ37_RS08310 (LNQ37_008305) 1861949..1862452 + 504 WP_248578091.1 thiol peroxidase -
LNQ37_RS08315 (LNQ37_008310) 1862487..1864094 - 1608 WP_038251390.1 transcriptional regulator TyrR -
LNQ37_RS08320 (LNQ37_008315) 1864412..1864858 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
LNQ37_RS08325 (LNQ37_008320) 1864872..1865330 + 459 WP_038242633.1 RES domain-containing protein Toxin
LNQ37_RS08330 (LNQ37_008325) 1865334..1866392 - 1059 WP_038242635.1 YcjF family protein -
LNQ37_RS08335 (LNQ37_008330) 1866389..1867786 - 1398 WP_004717556.1 YcjX family protein -
LNQ37_RS08340 (LNQ37_008335) 1867767..1868009 - 243 WP_087931058.1 phage shock protein PspD -
LNQ37_RS08345 (LNQ37_008340) 1868073..1868432 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
LNQ37_RS08350 (LNQ37_008345) 1868432..1868659 - 228 WP_038242637.1 envelope stress response membrane protein PspB -
LNQ37_RS08355 (LNQ37_008350) 1868743..1869408 - 666 WP_004717561.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17072.55 Da        Isoelectric Point: 6.6384

>T249485 WP_038242633.1 NZ_CP099811:1864872-1865330 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT249485 WP_038242631.1 NZ_CP099811:1864412-1864858 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References