249482

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3153927..3155647 Replicon chromosome
Accession NZ_CP099809
Organism Yersinia ruckeri strain NVI-10587

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LNQ46_RS14450 Protein ID WP_096823271.1
Coordinates 3154991..3155647 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LNQ46_RS14445 Protein ID WP_096823272.1
Coordinates 3153927..3154994 (-) Length 356 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ46_RS14395 (LNQ46_014390) 3150173..3150346 - 174 Protein_2791 type IV toxin-antitoxin system YeeU family antitoxin -
LNQ46_RS14400 (LNQ46_014395) 3150372..3150497 - 126 Protein_2792 antirestriction protein -
LNQ46_RS14405 (LNQ46_014400) 3150865..3151815 - 951 WP_038275283.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
LNQ46_RS14410 (LNQ46_014405) 3151808..3152203 - 396 WP_038245317.1 DUF6088 family protein -
LNQ46_RS14415 (LNQ46_014410) 3152278..3152508 - 231 Protein_2795 DUF4942 domain-containing protein -
LNQ46_RS14420 (LNQ46_014415) 3152658..3152786 + 129 Protein_2796 helix-turn-helix domain-containing protein -
LNQ46_RS14425 (LNQ46_014420) 3152779..3152899 + 121 Protein_2797 transposase -
LNQ46_RS14430 (LNQ46_014425) 3152928..3153224 - 297 Protein_2798 integrase core domain-containing protein -
LNQ46_RS14435 (LNQ46_014430) 3153223..3153621 + 399 Protein_2799 integrase core domain-containing protein -
LNQ46_RS14440 (LNQ46_014435) 3153640..3153906 - 267 Protein_2800 hypothetical protein -
LNQ46_RS14445 (LNQ46_014440) 3153927..3154994 - 1068 WP_096823272.1 macro domain-containing protein Antitoxin
LNQ46_RS14450 (LNQ46_014445) 3154991..3155647 - 657 WP_096823271.1 DUF4433 domain-containing protein Toxin
LNQ46_RS14455 (LNQ46_014450) 3155650..3156225 - 576 WP_071706520.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LNQ46_RS14460 (LNQ46_014455) 3156349..3156738 - 390 WP_248578898.1 restriction endonuclease subunit S -
LNQ46_RS14465 (LNQ46_014460) 3157002..3157292 - 291 WP_038275268.1 type II toxin-antitoxin system RelE/ParE family toxin -
LNQ46_RS14470 (LNQ46_014465) 3157282..3157536 - 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
LNQ46_RS14475 (LNQ46_014470) 3157710..3158969 - 1260 Protein_2807 integrase arm-type DNA-binding domain-containing protein -
LNQ46_RS14480 (LNQ46_014475) 3159483..3160427 + 945 WP_248578899.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3152928..3185208 32280
- flank IS/Tn - - 3152928..3153176 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(17-217)

Antitoxin

(18-129)


Sequences


Toxin        


Download         Length: 219 a.a.        Molecular weight: 25214.72 Da        Isoelectric Point: 6.6007

>T249482 WP_096823271.1 NZ_CP099809:c3155647-3154991 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLANYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp


Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40847.21 Da        Isoelectric Point: 6.3136

>AT249482 WP_096823272.1 NZ_CP099809:c3154994-3153927 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References