Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | sanaTA/AbiEii-DUF6088 |
| Location | 3150865..3152203 | Replicon | chromosome |
| Accession | NZ_CP099809 | ||
| Organism | Yersinia ruckeri strain NVI-10587 | ||
Toxin (Protein)
| Gene name | sanaT | Uniprot ID | - |
| Locus tag | LNQ46_RS14405 | Protein ID | WP_038275283.1 |
| Coordinates | 3150865..3151815 (-) | Length | 317 a.a. |
Antitoxin (Protein)
| Gene name | sanaA | Uniprot ID | A0A848MNT5 |
| Locus tag | LNQ46_RS14410 | Protein ID | WP_038245317.1 |
| Coordinates | 3151808..3152203 (-) | Length | 132 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LNQ46_RS14385 (LNQ46_014380) | 3147676..3148368 | - | 693 | WP_038245321.1 | oligogalacturonate-specific porin KdgM family protein | - |
| LNQ46_RS14390 (LNQ46_014385) | 3148416..3149570 | - | 1155 | WP_038245380.1 | N-acetylneuraminate epimerase | - |
| LNQ46_RS14395 (LNQ46_014390) | 3150173..3150346 | - | 174 | Protein_2791 | type IV toxin-antitoxin system YeeU family antitoxin | - |
| LNQ46_RS14400 (LNQ46_014395) | 3150372..3150497 | - | 126 | Protein_2792 | antirestriction protein | - |
| LNQ46_RS14405 (LNQ46_014400) | 3150865..3151815 | - | 951 | WP_038275283.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| LNQ46_RS14410 (LNQ46_014405) | 3151808..3152203 | - | 396 | WP_038245317.1 | DUF6088 family protein | Antitoxin |
| LNQ46_RS14415 (LNQ46_014410) | 3152278..3152508 | - | 231 | Protein_2795 | DUF4942 domain-containing protein | - |
| LNQ46_RS14420 (LNQ46_014415) | 3152658..3152786 | + | 129 | Protein_2796 | helix-turn-helix domain-containing protein | - |
| LNQ46_RS14425 (LNQ46_014420) | 3152779..3152899 | + | 121 | Protein_2797 | transposase | - |
| LNQ46_RS14430 (LNQ46_014425) | 3152928..3153224 | - | 297 | Protein_2798 | integrase core domain-containing protein | - |
| LNQ46_RS14435 (LNQ46_014430) | 3153223..3153621 | + | 399 | Protein_2799 | integrase core domain-containing protein | - |
| LNQ46_RS14440 (LNQ46_014435) | 3153640..3153906 | - | 267 | Protein_2800 | hypothetical protein | - |
| LNQ46_RS14445 (LNQ46_014440) | 3153927..3154994 | - | 1068 | WP_096823272.1 | macro domain-containing protein | - |
| LNQ46_RS14450 (LNQ46_014445) | 3154991..3155647 | - | 657 | WP_096823271.1 | DUF4433 domain-containing protein | - |
| LNQ46_RS14455 (LNQ46_014450) | 3155650..3156225 | - | 576 | WP_071706520.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
| LNQ46_RS14460 (LNQ46_014455) | 3156349..3156738 | - | 390 | WP_248578898.1 | restriction endonuclease subunit S | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 3152928..3153176 | 248 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 317 a.a. Molecular weight: 36088.43 Da Isoelectric Point: 4.5996
>T249481 WP_038275283.1 NZ_CP099809:c3151815-3150865 [Yersinia ruckeri]
MDDLTKLFPDVADALGIESVSIVEKDYYIVELLRLLQPMDFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPVAGFTQ
QYSRGQRKDIRKGIIRTVIETITASGTFRMDEGYPKVTRDEYRYNEIPVRYPQEYVQVPCLRPFIKLELMETDLLEAAEN
RAISSLVMDLTKKGEVVRAFPCATIGSTQAEKLISMMRRTAASMRDVERAVDESLVRHIYDNFCIVREKGADVPVLKQFV
QECIEQDIERYGAQYPEFCESPVEELKMGLEELVSNPVYKERYLQFVTPMVFGESHVSWEEAYACFRKTVLDVVDA
MDDLTKLFPDVADALGIESVSIVEKDYYIVELLRLLQPMDFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPVAGFTQ
QYSRGQRKDIRKGIIRTVIETITASGTFRMDEGYPKVTRDEYRYNEIPVRYPQEYVQVPCLRPFIKLELMETDLLEAAEN
RAISSLVMDLTKKGEVVRAFPCATIGSTQAEKLISMMRRTAASMRDVERAVDESLVRHIYDNFCIVREKGADVPVLKQFV
QECIEQDIERYGAQYPEFCESPVEELKMGLEELVSNPVYKERYLQFVTPMVFGESHVSWEEAYACFRKTVLDVVDA
Download Length: 951 bp
Antitoxin
Download Length: 132 a.a. Molecular weight: 14406.76 Da Isoelectric Point: 11.0360
>AT249481 WP_038245317.1 NZ_CP099809:c3152203-3151808 [Yersinia ruckeri]
MTTKARIQLRLKRSKRYVFTRDDFKDLAGYDQIGRALRELVKEGQLLKVGYGVYTKARQNVITGKLMPAAPGGSAAVVIE
ALERLKVDYRLVGATSAYNSGKSTQIPASLEIKTSPRFKRTLSVGSSKLNG
MTTKARIQLRLKRSKRYVFTRDDFKDLAGYDQIGRALRELVKEGQLLKVGYGVYTKARQNVITGKLMPAAPGGSAAVVIE
ALERLKVDYRLVGATSAYNSGKSTQIPASLEIKTSPRFKRTLSVGSSKLNG
Download Length: 396 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|