Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1919677..1920595 Replicon chromosome
Accession NZ_CP099809
Organism Yersinia ruckeri strain NVI-10587

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LNQ46_RS08635 Protein ID WP_038242633.1
Coordinates 1920137..1920595 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag LNQ46_RS08630 Protein ID WP_038242631.1
Coordinates 1919677..1920123 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ46_RS08610 (LNQ46_008605) 1915375..1916079 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
LNQ46_RS08615 (LNQ46_008610) 1916090..1917064 - 975 WP_248578615.1 L-Ala-D/L-Glu epimerase -
LNQ46_RS08620 (LNQ46_008615) 1917214..1917717 + 504 WP_004717547.1 thiol peroxidase -
LNQ46_RS08625 (LNQ46_008620) 1917752..1919359 - 1608 WP_038251390.1 transcriptional regulator TyrR -
LNQ46_RS08630 (LNQ46_008625) 1919677..1920123 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
LNQ46_RS08635 (LNQ46_008630) 1920137..1920595 + 459 WP_038242633.1 RES domain-containing protein Toxin
LNQ46_RS08640 (LNQ46_008635) 1920599..1921657 - 1059 WP_248578616.1 YcjF family protein -
LNQ46_RS08645 (LNQ46_008640) 1921654..1923051 - 1398 WP_004717556.1 YcjX family protein -
LNQ46_RS08650 (LNQ46_008645) 1923032..1923274 - 243 WP_087931058.1 phage shock protein PspD -
LNQ46_RS08655 (LNQ46_008650) 1923338..1923697 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
LNQ46_RS08660 (LNQ46_008655) 1923697..1923924 - 228 WP_248578617.1 envelope stress response membrane protein PspB -
LNQ46_RS08665 (LNQ46_008660) 1924008..1924673 - 666 WP_004717561.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17072.55 Da        Isoelectric Point: 6.6384

>T249476 WP_038242633.1 NZ_CP099809:1920137-1920595 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT249476 WP_038242631.1 NZ_CP099809:1919677-1920123 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References