Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 723462..724131 Replicon chromosome
Accession NZ_CP099809
Organism Yersinia ruckeri strain NVI-10587

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag LNQ46_RS03215 Protein ID WP_038241020.1
Coordinates 723709..724131 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LNQ46_RS03210 Protein ID WP_004719196.1
Coordinates 723462..723728 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ46_RS03195 (LNQ46_003195) 720799..721055 - 257 Protein_618 HD domain-containing protein -
LNQ46_RS03200 (LNQ46_003200) 721372..722037 + 666 WP_175537887.1 hemolysin III family protein -
LNQ46_RS03205 (LNQ46_003205) 722176..723168 - 993 WP_038241018.1 tRNA-modifying protein YgfZ -
LNQ46_RS03210 (LNQ46_003210) 723462..723728 + 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
LNQ46_RS03215 (LNQ46_003215) 723709..724131 + 423 WP_038241020.1 protein YgfX Toxin
LNQ46_RS03220 (LNQ46_003220) 724279..724797 - 519 WP_038241022.1 flavodoxin FldB -
LNQ46_RS03225 (LNQ46_003225) 724905..725804 + 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
LNQ46_RS03230 (LNQ46_003230) 725836..726552 + 717 WP_038276201.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LNQ46_RS03235 (LNQ46_003235) 726559..728292 + 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T249474 WP_038241020.1 NZ_CP099809:723709-724131 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT249474 WP_004719196.1 NZ_CP099809:723462-723728 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References