Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 545229..545951 Replicon chromosome
Accession NZ_CP099809
Organism Yersinia ruckeri strain NVI-10587

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag LNQ46_RS02370 Protein ID WP_248578805.1
Coordinates 545631..545951 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LNQ46_RS02365 Protein ID WP_248578840.1
Coordinates 545229..545564 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ46_RS02340 (LNQ46_002340) 540826..541680 - 855 WP_248578686.1 DNA adenine methylase -
LNQ46_RS02345 (LNQ46_002345) 541751..543220 - 1470 WP_248578685.1 hypothetical protein -
LNQ46_RS02350 (LNQ46_002350) 543496..543693 + 198 Protein_452 50S ribosome-binding GTPase -
LNQ46_RS02355 (LNQ46_002355) 543755..544905 + 1151 WP_087931031.1 IS3 family transposase -
LNQ46_RS02360 (LNQ46_002360) 544925..545215 + 291 Protein_454 JAB domain-containing protein -
LNQ46_RS02365 (LNQ46_002365) 545229..545564 + 336 WP_248578840.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LNQ46_RS02370 (LNQ46_002370) 545631..545951 + 321 WP_248578805.1 TA system toxin CbtA family protein Toxin
LNQ46_RS02375 (LNQ46_002375) 546065..546898 + 834 WP_248578806.1 DUF4942 domain-containing protein -
LNQ46_RS02380 (LNQ46_002380) 547095..548174 - 1080 WP_248578807.1 tyrosine-type recombinase/integrase -
LNQ46_RS02385 (LNQ46_002385) 548174..548737 - 564 WP_248578808.1 PH domain-containing protein -
LNQ46_RS02390 (LNQ46_002390) 548763..549338 - 576 WP_248578809.1 phage repressor protein CI -
LNQ46_RS02395 (LNQ46_002395) 549456..549677 + 222 WP_248578810.1 regulator -
LNQ46_RS02400 (LNQ46_002400) 549709..550218 + 510 WP_248578811.1 phage regulatory CII family protein -
LNQ46_RS02405 (LNQ46_002405) 550226..550447 + 222 WP_004717258.1 DUF2724 domain-containing protein -
LNQ46_RS02410 (LNQ46_002410) 550434..550808 + 375 WP_248578812.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - rfaE 523447..608247 84800


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(7-105)

Antitoxin

Antitoxin CbeA

(8-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12056.64 Da        Isoelectric Point: 5.0486

>T249473 WP_248578805.1 NZ_CP099809:545631-545951 [Yersinia ruckeri]
MQTTTVPATLPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDASIEEHIEAGITLADAVNFLVERYELVRTDRKGF
TWQEQTPFLTATDILRAKRATGLMNT

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12410.07 Da        Isoelectric Point: 6.0538

>AT249473 WP_248578840.1 NZ_CP099809:545229-545564 [Yersinia ruckeri]
MNKDATQIWGLNRDITPCFGARLVQEGNSLHFLADRAGFNGSFSKMQARDLDEAFPHFVAHMELMLLSGELNPRYSHCVT
LYRNGLTCEADTLGSYGYVYIAIYPSNLVTA

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References