Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2992863..2993532 Replicon chromosome
Accession NZ_CP099808
Organism Yersinia ruckeri strain NVI-11076

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LNQ41_RS13730 Protein ID WP_045844283.1
Coordinates 2992863..2993285 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LNQ41_RS13735 Protein ID WP_004719196.1
Coordinates 2993266..2993532 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ41_RS13710 (LNQ41_013705) 2988702..2990435 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
LNQ41_RS13715 (LNQ41_013710) 2990442..2991158 - 717 WP_071667006.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LNQ41_RS13720 (LNQ41_013715) 2991190..2992089 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
LNQ41_RS13725 (LNQ41_013720) 2992197..2992715 + 519 WP_038241022.1 flavodoxin FldB -
LNQ41_RS13730 (LNQ41_013725) 2992863..2993285 - 423 WP_045844283.1 protein YgfX Toxin
LNQ41_RS13735 (LNQ41_013730) 2993266..2993532 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
LNQ41_RS13740 (LNQ41_013735) 2993826..2994818 + 993 WP_038241018.1 tRNA-modifying protein YgfZ -
LNQ41_RS13745 (LNQ41_013740) 2994957..2995622 - 666 WP_175537887.1 hemolysin III family protein -
LNQ41_RS13750 (LNQ41_013745) 2995939..2996195 + 257 Protein_2662 HD domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 16520.52 Da        Isoelectric Point: 11.3725

>T249472 WP_045844283.1 NZ_CP099808:c2993285-2992863 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGRRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT249472 WP_004719196.1 NZ_CP099808:c2993532-2993266 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References