Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1935698..1936616 Replicon chromosome
Accession NZ_CP099808
Organism Yersinia ruckeri strain NVI-11076

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LNQ41_RS08710 Protein ID WP_248594018.1
Coordinates 1936158..1936616 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag LNQ41_RS08705 Protein ID WP_038242631.1
Coordinates 1935698..1936144 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ41_RS08685 (LNQ41_008680) 1931396..1932100 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
LNQ41_RS08690 (LNQ41_008685) 1932111..1933085 - 975 WP_071666721.1 L-Ala-D/L-Glu epimerase -
LNQ41_RS08695 (LNQ41_008690) 1933235..1933738 + 504 WP_004717547.1 thiol peroxidase -
LNQ41_RS08700 (LNQ41_008695) 1933773..1935380 - 1608 WP_038251390.1 transcriptional regulator TyrR -
LNQ41_RS08705 (LNQ41_008700) 1935698..1936144 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
LNQ41_RS08710 (LNQ41_008705) 1936158..1936616 + 459 WP_248594018.1 RES domain-containing protein Toxin
LNQ41_RS08715 (LNQ41_008710) 1936620..1937678 - 1059 WP_038242635.1 YcjF family protein -
LNQ41_RS08720 (LNQ41_008715) 1937675..1939072 - 1398 WP_004717556.1 YcjX family protein -
LNQ41_RS08725 (LNQ41_008720) 1939053..1939295 - 243 WP_099511574.1 phage shock protein PspD -
LNQ41_RS08730 (LNQ41_008725) 1939359..1939718 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
LNQ41_RS08735 (LNQ41_008730) 1939718..1939945 - 228 WP_038242637.1 envelope stress response membrane protein PspB -
LNQ41_RS08740 (LNQ41_008735) 1940029..1940694 - 666 WP_004717561.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17068.56 Da        Isoelectric Point: 6.6384

>T249467 WP_248594018.1 NZ_CP099808:1936158-1936616 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPPPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT249467 WP_038242631.1 NZ_CP099808:1935698-1936144 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References