Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 513794..514328 Replicon chromosome
Accession NZ_CP099808
Organism Yersinia ruckeri strain NVI-11076

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LNQ41_RS02360 Protein ID WP_038245762.1
Coordinates 514038..514328 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A1JJ37
Locus tag LNQ41_RS02355 Protein ID WP_005175264.1
Coordinates 513794..514048 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNQ41_RS02345 (LNQ41_002345) 509598..512387 - 2790 Protein_454 STY4851/ECs_5259 family protein -
LNQ41_RS02355 (LNQ41_002355) 513794..514048 + 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LNQ41_RS02360 (LNQ41_002360) 514038..514328 + 291 WP_038245762.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LNQ41_RS02365 (LNQ41_002365) 514592..515059 + 468 WP_051847072.1 restriction endonuclease subunit S -
LNQ41_RS02370 (LNQ41_002370) 515106..515681 + 576 WP_038245760.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LNQ41_RS02375 (LNQ41_002375) 515684..516340 + 657 WP_038245758.1 DUF4433 domain-containing protein -
LNQ41_RS02380 (LNQ41_002380) 516337..517404 + 1068 WP_038245756.1 macro domain-containing protein -
LNQ41_RS02385 (LNQ41_002385) 517425..517691 + 267 Protein_462 hypothetical protein -
LNQ41_RS02390 (LNQ41_002390) 517710..518108 - 399 Protein_463 integrase core domain-containing protein -
LNQ41_RS02395 (LNQ41_002395) 518107..518403 + 297 Protein_464 integrase core domain-containing protein -
LNQ41_RS02400 (LNQ41_002400) 518432..518537 - 106 Protein_465 transposase -
LNQ41_RS02405 (LNQ41_002405) 518551..518679 - 129 Protein_466 helix-turn-helix domain-containing protein -
LNQ41_RS02410 (LNQ41_002410) 518829..519059 + 231 Protein_467 DUF4942 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 513794..523663 9869
- inside IScluster/Tn - - 512408..518403 5995


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11494.42 Da        Isoelectric Point: 9.9816

>T249464 WP_038245762.1 NZ_CP099808:514038-514328 [Yersinia ruckeri]
MTFNIDFDERALKEWHKLDKTIREQFKKKLRKLQENPYIESARLHGDLAGCFKIKLRASGFRLIYQVIDEEIVIWIVAVG
KREDEKAYDLAKKRIQ

Download         Length: 291 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9680.07 Da        Isoelectric Point: 4.8283

>AT249464 WP_005175264.1 NZ_CP099808:513794-514048 [Yersinia ruckeri]
MSTIQIRVDDELKKSAYQAFEKLNLSPSDALRLFLRYVAENEKLPFSEVSVMVSNQDEDADILAVVRERLKNPAKRIRVN
IDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A1JJ37

References