Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1921411..1922329 Replicon chromosome
Accession NZ_CP099805
Organism Yersinia ruckeri strain NVI-10705

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LOR96_RS08745 Protein ID WP_038242633.1
Coordinates 1921871..1922329 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A085U7R3
Locus tag LOR96_RS08740 Protein ID WP_038242631.1
Coordinates 1921411..1921857 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOR96_RS08720 (LOR96_008710) 1917109..1917813 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
LOR96_RS08725 (LOR96_008715) 1917824..1918798 - 975 WP_071706618.1 L-Ala-D/L-Glu epimerase -
LOR96_RS08730 (LOR96_008720) 1918948..1919451 + 504 WP_004717547.1 thiol peroxidase -
LOR96_RS08735 (LOR96_008725) 1919486..1921093 - 1608 WP_096823414.1 transcriptional regulator TyrR -
LOR96_RS08740 (LOR96_008730) 1921411..1921857 + 447 WP_038242631.1 DUF2384 domain-containing protein Antitoxin
LOR96_RS08745 (LOR96_008735) 1921871..1922329 + 459 WP_038242633.1 RES domain-containing protein Toxin
LOR96_RS08750 (LOR96_008740) 1922333..1923391 - 1059 WP_038242635.1 YcjF family protein -
LOR96_RS08755 (LOR96_008745) 1923388..1924785 - 1398 WP_004717556.1 YcjX family protein -
LOR96_RS08760 (LOR96_008750) 1924766..1925008 - 243 WP_096823415.1 phage shock protein PspD -
LOR96_RS08765 (LOR96_008755) 1925072..1925431 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
LOR96_RS08770 (LOR96_008760) 1925431..1925658 - 228 WP_038242637.1 envelope stress response membrane protein PspB -
LOR96_RS08775 (LOR96_008765) 1925742..1926407 - 666 WP_038275968.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-145)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17072.55 Da        Isoelectric Point: 6.6384

>T249456 WP_038242633.1 NZ_CP099805:1921871-1922329 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16406.87 Da        Isoelectric Point: 8.0956

>AT249456 WP_038242631.1 NZ_CP099805:1921411-1921857 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWMSMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A085U7R3

References