Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 256538..256809 Replicon chromosome
Accession NZ_CP099752
Organism Escherichia coli strain 806883-11-2019

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 256668..256771 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 256538..256809 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHF43_RS01290 253093..253755 - 663 WP_000944256.1 exodeoxyribonuclease X -
NHF43_RS01295 253779..254435 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
NHF43_RS01300 254537..254767 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NHF43_RS01305 254906..255280 + 375 WP_000204699.1 CopC domain-containing protein YobA -
NHF43_RS01310 255284..256156 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
NHF43_RS01315 256169..256510 + 342 WP_000976492.1 YebY family protein -
- 256538..256809 - 272 - - Antitoxin
- 256668..256771 + 104 - - Toxin
NHF43_RS01320 256906..257562 + 657 Protein_255 protein-serine/threonine phosphatase -
NHF43_RS01325 257563..257754 - 192 WP_001296140.1 YebW family protein -
NHF43_RS01330 257859..258095 - 237 WP_001295499.1 YebV family protein -
NHF43_RS01335 258213..259652 - 1440 WP_112013667.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T249396 NZ_CP099752:256668-256771 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT249396 NZ_CP099752:c256809-256538 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References