Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1876010..1876155 Replicon chromosome
Accession NZ_CP099743
Organism Klebsiella pneumoniae strain 503666-2-2019

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1876046..1876148 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1876010..1876155 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHF44_RS09075 (NHF44_09070) 1871140..1873200 + 2061 WP_004151449.1 oligopeptidase B -
NHF44_RS09080 (NHF44_09075) 1873204..1873863 - 660 WP_021440386.1 exodeoxyribonuclease X -
NHF44_RS09085 (NHF44_09080) 1873942..1874172 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NHF44_RS09090 (NHF44_09085) 1874285..1874659 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NHF44_RS09095 (NHF44_09090) 1874663..1875532 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NHF44_RS09100 (NHF44_09095) 1875549..1875887 + 339 WP_002911404.1 YebY family protein -
- 1876010..1876155 - 146 - - Antitoxin
- 1876046..1876148 + 103 - - Toxin
NHF44_RS09105 (NHF44_09100) 1876524..1876667 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NHF44_RS09110 (NHF44_09105) 1876772..1877740 - 969 WP_004151446.1 VirK/YbjX family protein -
NHF44_RS09115 (NHF44_09110) 1877897..1878550 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NHF44_RS09120 (NHF44_09115) 1878547..1878738 - 192 WP_002911395.1 YebW family protein -
NHF44_RS09125 (NHF44_09120) 1878836..1879075 - 240 WP_002911393.1 YebV family protein -
NHF44_RS09130 (NHF44_09125) 1879191..1880624 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T249360 NZ_CP099743:1876046-1876148 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT249360 NZ_CP099743:c1876155-1876010 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References