Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1721493..1722049 Replicon chromosome
Accession NZ_CP099735
Organism Photobacterium sp. TY1-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NH461_RS24475 Protein ID WP_261603562.1
Coordinates 1721738..1722049 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NH461_RS24470 Protein ID WP_261603561.1
Coordinates 1721493..1721750 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NH461_RS24440 (NH461_24370) 1716696..1717214 + 519 WP_261603555.1 cysteine hydrolase family protein -
NH461_RS24445 (NH461_24375) 1717338..1717955 - 618 WP_261603556.1 SCO family protein -
NH461_RS24450 (NH461_24380) 1717948..1718349 - 402 WP_261603557.1 hypothetical protein -
NH461_RS24455 (NH461_24385) 1718342..1718911 - 570 WP_261603558.1 hypothetical protein -
NH461_RS24460 (NH461_24390) 1718922..1720103 - 1182 WP_261603559.1 MFS transporter -
NH461_RS24465 (NH461_24395) 1720284..1721258 + 975 WP_261603560.1 LysR family transcriptional regulator -
NH461_RS24470 (NH461_24400) 1721493..1721750 + 258 WP_261603561.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NH461_RS24475 (NH461_24405) 1721738..1722049 + 312 WP_261603562.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NH461_RS24480 (NH461_24410) 1722152..1722562 - 411 WP_261604628.1 VF530 family DNA-binding protein -
NH461_RS24485 (NH461_24415) 1722782..1723711 + 930 WP_261603563.1 hypothetical protein -
NH461_RS24490 (NH461_24420) 1723967..1724419 + 453 WP_261603564.1 TlpA disulfide reductase family protein -
NH461_RS24495 (NH461_24425) 1724495..1725748 + 1254 WP_261603565.1 sialidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11876.71 Da        Isoelectric Point: 4.8893

>T249355 WP_261603562.1 NZ_CP099735:1721738-1722049 [Photobacterium sp. TY1-4]
MAEVIWTDPALSDLNETAEYIALDNLVAAKLLVQSVFEKVERLELFPGSGRVPPELQHLSYREVVVSLCRVFYKQEGDKV
FILHVMREERDLRKFLLSQQSSP

Download         Length: 312 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9622.11 Da        Isoelectric Point: 6.7275

>AT249355 WP_261603561.1 NZ_CP099735:1721493-1721750 [Photobacterium sp. TY1-4]
MKVELVTSLKRQATKILADLHDSKEPVLITEHGKPSAYLVDVEDYEFMQNRLAMLEGIARGERAIAEGNVTPHSEAKEKM
SKWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References