Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 579677..580205 Replicon chromosome
Accession NZ_CP099735
Organism Photobacterium sp. TY1-4

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag NH461_RS19310 Protein ID WP_261604229.1
Coordinates 579677..579958 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NH461_RS19315 Protein ID WP_261604230.1
Coordinates 579951..580205 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NH461_RS19280 (NH461_19230) 576518..576841 - 324 WP_261604224.1 hypothetical protein -
NH461_RS19285 (NH461_19235) 576916..577377 - 462 WP_261604225.1 hypothetical protein -
NH461_RS19290 (NH461_19240) 577540..578010 - 471 WP_261604226.1 hypothetical protein -
NH461_RS19295 (NH461_19245) 578137..578622 - 486 WP_261604227.1 GNAT family N-acetyltransferase -
NH461_RS19300 (NH461_19250) 578786..579286 - 501 WP_261604228.1 GNAT family N-acetyltransferase -
NH461_RS19305 (NH461_19255) 579387..579536 + 150 Protein_550 IS110 family transposase -
NH461_RS19310 (NH461_19260) 579677..579958 - 282 WP_261604229.1 Txe/YoeB family addiction module toxin Toxin
NH461_RS19315 (NH461_19265) 579951..580205 - 255 WP_261604230.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NH461_RS19320 (NH461_19270) 580393..580660 + 268 Protein_553 IS110 family transposase -
NH461_RS19325 (NH461_19275) 580866..582461 - 1596 WP_261604231.1 hypothetical protein -
NH461_RS19330 (NH461_19280) 582577..582972 - 396 WP_261604232.1 hypothetical protein -
NH461_RS19335 (NH461_19285) 583048..583369 + 322 Protein_556 hypothetical protein -
NH461_RS19340 (NH461_19290) 583692..584123 - 432 WP_261604233.1 hypothetical protein -
NH461_RS19345 (NH461_19295) 584281..584806 + 526 Protein_558 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 177987..610045 432058


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(12-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11012.50 Da        Isoelectric Point: 8.0108

>T249354 WP_261604229.1 NZ_CP099735:c579958-579677 [Photobacterium sp. TY1-4]
MSRMLAWTDAAWTDAAWDDYLYWQSQDKKTLKRINKLIVDTKRSPFEGIGKPEALKENLSGFWSRRIDESNRLVYAVDNI
HITIISCRYHYEA

Download         Length: 282 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9390.61 Da        Isoelectric Point: 4.7777

>AT249354 WP_261604230.1 NZ_CP099735:c580205-579951 [Photobacterium sp. TY1-4]
MRIVSFTEARNGLKSVLDGVVNDADCTVITRRDSEDAVVMSMDYYNSLMETVHLLKSPANAAHINKSIEQYKAGKVTERD
IIDE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References