Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 579677..580205 Replicon chromosome
Accession NZ_CP099735
Organism Photobacterium sp. TY1-4

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag NH461_RS19310 Protein ID WP_261604229.1
Coordinates 579677..579958 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag NH461_RS19315 Protein ID WP_261604230.1
Coordinates 579951..580205 (-) Length 85 a.a.

Genomic Context

NH461_RS19305NH461_RS19320NH461_RS19335NH461_RS19345NH461_RS19280NH461_RS19285NH461_RS19290NH461_RS19295NH461_RS19300NH461_RS19310NH461_RS19315NH461_RS19325NH461_RS19330NH461_RS19340
Location: 579387..579536 (150 bp)
Type: Others
Protein ID: Protein_550
Location: 580393..580660 (268 bp)
Type: Others
Protein ID: Protein_553
Location: 583048..583369 (322 bp)
Type: Others
Protein ID: Protein_556
Location: 584281..584806 (526 bp)
Type: Others
Protein ID: Protein_558
Location: 576518..576841 (324 bp)
Type: Others
Protein ID: WP_261604224.1
Location: 576916..577377 (462 bp)
Type: Others
Protein ID: WP_261604225.1
Location: 577540..578010 (471 bp)
Type: Others
Protein ID: WP_261604226.1
Location: 578137..578622 (486 bp)
Type: Others
Protein ID: WP_261604227.1
Location: 578786..579286 (501 bp)
Type: Others
Protein ID: WP_261604228.1
Location: 579677..579958 (282 bp)
Type: Toxin
Protein ID: WP_261604229.1
Location: 579951..580205 (255 bp)
Type: Antitoxin
Protein ID: WP_261604230.1
Location: 580866..582461 (1596 bp)
Type: Others
Protein ID: WP_261604231.1
Location: 582577..582972 (396 bp)
Type: Others
Protein ID: WP_261604232.1
Location: 583692..584123 (432 bp)
Type: Others
Protein ID: WP_261604233.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NH461_RS19280 (NH461_19230)576518..576841-324WP_261604224.1hypothetical protein-
NH461_RS19285 (NH461_19235)576916..577377-462WP_261604225.1hypothetical protein-
NH461_RS19290 (NH461_19240)577540..578010-471WP_261604226.1hypothetical protein-
NH461_RS19295 (NH461_19245)578137..578622-486WP_261604227.1GNAT family N-acetyltransferase-
NH461_RS19300 (NH461_19250)578786..579286-501WP_261604228.1GNAT family N-acetyltransferase-
NH461_RS19305 (NH461_19255)579387..579536+150Protein_550IS110 family transposase-
NH461_RS19310 (NH461_19260)579677..579958-282WP_261604229.1Txe/YoeB family addiction module toxinToxin
NH461_RS19315 (NH461_19265)579951..580205-255WP_261604230.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
NH461_RS19320 (NH461_19270)580393..580660+268Protein_553IS110 family transposase-
NH461_RS19325 (NH461_19275)580866..582461-1596WP_261604231.1hypothetical protein-
NH461_RS19330 (NH461_19280)582577..582972-396WP_261604232.1hypothetical protein-
NH461_RS19335 (NH461_19285)583048..583369+322Protein_556hypothetical protein-
NH461_RS19340 (NH461_19290)583692..584123-432WP_261604233.1hypothetical protein-
NH461_RS19345 (NH461_19295)584281..584806+526Protein_558IS3 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--177987..610045432058


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(12-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11012.50 Da        Isoelectric Point: 8.0108

>T249354 WP_261604229.1 NZ_CP099735:c579958-579677 [Photobacterium sp. TY1-4]
MSRMLAWTDAAWTDAAWDDYLYWQSQDKKTLKRINKLIVDTKRSPFEGIGKPEALKENLSGFWSRRIDESNRLVYAVDNI
HITIISCRYHYEA

Download         Length: 282 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9390.61 Da        Isoelectric Point: 4.7777

>AT249354 WP_261604230.1 NZ_CP099735:c580205-579951 [Photobacterium sp. TY1-4]
MRIVSFTEARNGLKSVLDGVVNDADCTVITRRDSEDAVVMSMDYYNSLMETVHLLKSPANAAHINKSIEQYKAGKVTERD
IIDE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References