Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2849846..2850477 Replicon chromosome
Accession NZ_CP099734
Organism Photobacterium sp. TY1-4

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag NH461_RS13335 Protein ID WP_261600819.1
Coordinates 2849846..2850232 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag NH461_RS13340 Protein ID WP_261600820.1
Coordinates 2850232..2850477 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NH461_RS13300 (NH461_13270) 2845233..2845589 + 357 WP_261600814.1 outer membrane protein assembly factor BamE -
NH461_RS13305 (NH461_13275) 2845706..2846053 - 348 WP_261600815.1 RnfH family protein -
NH461_RS13310 (NH461_13280) 2846043..2846477 - 435 WP_261600816.1 SRPBCC family protein -
NH461_RS13315 (NH461_13285) 2846673..2847155 + 483 WP_261600817.1 SsrA-binding protein SmpB -
NH461_RS13325 (NH461_13295) 2847688..2848643 - 956 Protein_2534 HipA domain-containing protein -
NH461_RS13335 (NH461_13305) 2849846..2850232 - 387 WP_261600819.1 HipA N-terminal domain-containing protein Toxin
NH461_RS13340 (NH461_13310) 2850232..2850477 - 246 WP_261600820.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
NH461_RS13345 (NH461_13315) 2850774..2851307 + 534 WP_261600821.1 hypothetical protein -
NH461_RS13350 (NH461_13320) 2851331..2853352 + 2022 WP_261600822.1 DNA phosphorothioation-associated putative methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2848639..2857148 8509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14675.72 Da        Isoelectric Point: 5.2301

>T249353 WP_261600819.1 NZ_CP099734:c2850232-2849846 [Photobacterium sp. TY1-4]
MASLIAYMNGECVGKLIKLADGAHHFQYAEEWIESPRGRPLSLSLPLQYQKLTSNCVINYFDNLLPDLNEIRDRIVARYN
ADSRQAFDLLKQVGKDSVGAISLHMPEERPAPKQLEYEVLDDRRLKDE

Download         Length: 387 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9623.08 Da        Isoelectric Point: 10.2030

>AT249353 WP_261600820.1 NZ_CP099734:c2850477-2850232 [Photobacterium sp. TY1-4]
MIYNSRQLANHLKLMRTRKHLTQAQLAKRVGIKQSTLSNFETNPETTQLQTFFKIIQALEVDLEVRERQKEVKPQIDDEV
W

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References