Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1574475..1575003 Replicon chromosome
Accession NZ_CP099734
Organism Photobacterium sp. TY1-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NH461_RS07400 Protein ID WP_261602592.1
Coordinates 1574713..1575003 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A193KIL6
Locus tag NH461_RS07395 Protein ID WP_017028225.1
Coordinates 1574475..1574723 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NH461_RS07375 (NH461_07365) 1570063..1570566 - 504 WP_261602589.1 DUF4174 domain-containing protein -
NH461_RS07380 (NH461_07370) 1570750..1571676 - 927 WP_261602590.1 LysR family transcriptional regulator -
NH461_RS07385 (NH461_07375) 1571863..1573056 + 1194 WP_261602591.1 glycine C-acetyltransferase -
NH461_RS07390 (NH461_07380) 1573176..1574207 + 1032 WP_255390276.1 L-threonine 3-dehydrogenase -
NH461_RS07395 (NH461_07385) 1574475..1574723 + 249 WP_017028225.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NH461_RS07400 (NH461_07390) 1574713..1575003 + 291 WP_261602592.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NH461_RS07405 (NH461_07395) 1575051..1575491 + 441 WP_261602593.1 DUF4113 domain-containing protein -
NH461_RS07410 (NH461_07400) 1575841..1576155 + 315 WP_261602594.1 hypothetical protein -
NH461_RS07415 (NH461_07405) 1576272..1577174 + 903 WP_261602595.1 hypothetical protein -
NH461_RS07420 (NH461_07410) 1577313..1578086 - 774 WP_261602596.1 IS21-like element helper ATPase IstB -
NH461_RS07425 (NH461_07415) 1578207..1579282 + 1076 WP_261602597.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1570750..1584509 13759


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11222.28 Da        Isoelectric Point: 10.6832

>T249352 WP_261602592.1 NZ_CP099734:1574713-1575003 [Photobacterium sp. TY1-4]
MTYKLDFKKSALKEWKKLGSTLQQMFKKKLIERLENPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDVVIVTVLAVGK
RERSDVYRKAMKRSDV

Download         Length: 291 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9061.33 Da        Isoelectric Point: 3.9610

>AT249352 WP_017028225.1 NZ_CP099734:1574475-1574723 [Photobacterium sp. TY1-4]
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMIDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A193KIL6

References