Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1574475..1575003 Replicon chromosome
Accession NZ_CP099734
Organism Photobacterium sp. TY1-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NH461_RS07400 Protein ID WP_261602592.1
Coordinates 1574713..1575003 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A193KIL6
Locus tag NH461_RS07395 Protein ID WP_017028225.1
Coordinates 1574475..1574723 (+) Length 83 a.a.

Genomic Context

NH461_RS07385NH461_RS07390NH461_RS07395NH461_RS07400NH461_RS07405NH461_RS07410NH461_RS07415NH461_RS07425NH461_RS07375NH461_RS07380NH461_RS07420
Location: 1571863..1573056 (1194 bp)
Type: Others
Protein ID: WP_261602591.1
Location: 1573176..1574207 (1032 bp)
Type: Others
Protein ID: WP_255390276.1
Location: 1574475..1574723 (249 bp)
Type: Antitoxin
Protein ID: WP_017028225.1
Location: 1574713..1575003 (291 bp)
Type: Toxin
Protein ID: WP_261602592.1
Location: 1575051..1575491 (441 bp)
Type: Others
Protein ID: WP_261602593.1
Location: 1575841..1576155 (315 bp)
Type: Others
Protein ID: WP_261602594.1
Location: 1576272..1577174 (903 bp)
Type: Others
Protein ID: WP_261602595.1
Location: 1578207..1579282 (1076 bp)
Type: Others
Protein ID: WP_261602597.1
Location: 1570063..1570566 (504 bp)
Type: Others
Protein ID: WP_261602589.1
Location: 1570750..1571676 (927 bp)
Type: Others
Protein ID: WP_261602590.1
Location: 1577313..1578086 (774 bp)
Type: Others
Protein ID: WP_261602596.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NH461_RS07375 (NH461_07365)1570063..1570566-504WP_261602589.1DUF4174 domain-containing protein-
NH461_RS07380 (NH461_07370)1570750..1571676-927WP_261602590.1LysR family transcriptional regulator-
NH461_RS07385 (NH461_07375)1571863..1573056+1194WP_261602591.1glycine C-acetyltransferase-
NH461_RS07390 (NH461_07380)1573176..1574207+1032WP_255390276.1L-threonine 3-dehydrogenase-
NH461_RS07395 (NH461_07385)1574475..1574723+249WP_017028225.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
NH461_RS07400 (NH461_07390)1574713..1575003+291WP_261602592.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NH461_RS07405 (NH461_07395)1575051..1575491+441WP_261602593.1DUF4113 domain-containing protein-
NH461_RS07410 (NH461_07400)1575841..1576155+315WP_261602594.1hypothetical protein-
NH461_RS07415 (NH461_07405)1576272..1577174+903WP_261602595.1hypothetical protein-
NH461_RS07420 (NH461_07410)1577313..1578086-774WP_261602596.1IS21-like element helper ATPase IstB-
NH461_RS07425 (NH461_07415)1578207..1579282+1076WP_261602597.1IS3 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1570750..158450913759


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11222.28 Da        Isoelectric Point: 10.6832

>T249352 WP_261602592.1 NZ_CP099734:1574713-1575003 [Photobacterium sp. TY1-4]
MTYKLDFKKSALKEWKKLGSTLQQMFKKKLIERLENPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDVVIVTVLAVGK
RERSDVYRKAMKRSDV

Download         Length: 291 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9061.33 Da        Isoelectric Point: 3.9610

>AT249352 WP_017028225.1 NZ_CP099734:1574475-1574723 [Photobacterium sp. TY1-4]
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMIDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A193KIL6

References