Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1199766..1200307 Replicon chromosome
Accession NZ_CP099712
Organism Dietzia kunjamensis strain 313

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NHB83_RS05620 Protein ID WP_253003415.1
Coordinates 1200041..1200307 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NHB83_RS05615 Protein ID WP_253003414.1
Coordinates 1199766..1200032 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHB83_RS05585 (NHB83_05585) 1195023..1195289 - 267 Protein_1083 dihydrofolate reductase family protein -
NHB83_RS05590 (NHB83_05590) 1195340..1195762 - 423 WP_253003410.1 nuclear transport factor 2 family protein -
NHB83_RS05595 (NHB83_05595) 1195822..1197210 + 1389 WP_253003411.1 carboxylesterase family protein -
NHB83_RS05605 (NHB83_05605) 1197439..1198989 + 1551 WP_253003412.1 cobyric acid synthase -
NHB83_RS05610 (NHB83_05610) 1198986..1199726 + 741 WP_253003413.1 cobalt-precorrin-6A reductase -
NHB83_RS05615 (NHB83_05615) 1199766..1200032 + 267 WP_253003414.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NHB83_RS05620 (NHB83_05620) 1200041..1200307 + 267 WP_253003415.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NHB83_RS05625 (NHB83_05625) 1200359..1201840 - 1482 WP_253003416.1 cobyrinate a,c-diamide synthase -
NHB83_RS05630 (NHB83_05630) 1201834..1202448 - 615 WP_253003417.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
NHB83_RS05635 (NHB83_05635) 1202448..1204682 - 2235 WP_253003418.1 magnesium chelatase subunit D family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(22-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10132.66 Da        Isoelectric Point: 9.8737

>T249307 WP_253003415.1 NZ_CP099712:1200041-1200307 [Dietzia kunjamensis]
VEDYELVVAPPAARAIQRGLPEKIAAAVVEFLTGPLIANPRRAGNELRRELTGVYFARRGTYRILYRIDDDAREVLVLRV
EHRRDVYR

Download         Length: 267 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9542.69 Da        Isoelectric Point: 4.8261

>AT249307 WP_253003414.1 NZ_CP099712:1199766-1200032 [Dietzia kunjamensis]
MSTEPLRDVRANFSDVVDRVSKHHERVTVTKNGRPVAVVMSPDDLAALEETLDVLSDPSALADIQEADAARTHGEVVRGV
DAVRALRP

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References