Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 72857..73452 Replicon plasmid unnamed4
Accession NZ_CP099648
Organism Paraburkholderia fungorum strain OTU2SAUBB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NHH62_RS41090 Protein ID WP_253045751.1
Coordinates 73162..73452 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NHH62_RS41085 Protein ID WP_253045749.1
Coordinates 72857..73165 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHH62_RS41060 (NHH62_41060) 68819..69499 - 681 WP_253045740.1 hypothetical protein -
NHH62_RS41065 (NHH62_41065) 69677..70648 - 972 WP_253045742.1 tyrosine-type recombinase/integrase -
NHH62_RS41070 (NHH62_41070) 70666..70857 - 192 WP_253045743.1 hypothetical protein -
NHH62_RS41075 (NHH62_41075) 71115..72008 + 894 WP_253045745.1 DNA-binding protein -
NHH62_RS41080 (NHH62_41080) 72039..72758 + 720 WP_253045747.1 hypothetical protein -
NHH62_RS41085 (NHH62_41085) 72857..73165 + 309 WP_253045749.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NHH62_RS41090 (NHH62_41090) 73162..73452 + 291 WP_253045751.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NHH62_RS41095 (NHH62_41095) 73476..74183 + 708 WP_253045753.1 ATP-binding protein -
NHH62_RS41100 (NHH62_41100) 74231..74743 + 513 WP_253045755.1 hypothetical protein -
NHH62_RS41105 (NHH62_41105) 74769..76085 + 1317 WP_253045757.1 IS701 family transposase -
NHH62_RS41110 (NHH62_41110) 76765..77322 + 558 WP_046565095.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..83927 83927


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-55)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11176.70 Da        Isoelectric Point: 4.8838

>T249287 WP_253045751.1 NZ_CP099648:73162-73452 [Paraburkholderia fungorum]
VRLEWSAFAIEDRDAIFDYIEEDRPRAAVVVDDRIRTQVRQLLQFPETGRPGRIEGTRELVISRTPYIAAYRITGDTVRI
LRVLHGAQLWPDEILD

Download         Length: 291 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10934.37 Da        Isoelectric Point: 5.1224

>AT249287 WP_253045749.1 NZ_CP099648:72857-73165 [Paraburkholderia fungorum]
MAASALVQTRIDPVLKERAAAVLDNMGLTVSDAVRILLTRVANEGALPFAFATDPAVHDAWFRAKVQEALDDPRPATPDD
DVEAHFARRRAAALRKAGEGDA

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References