Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2244238..2244842 Replicon chromosome
Accession NZ_CP099610
Organism Pseudomonas moraviensis strain OTU5VILLAA1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NF674_RS09980 Protein ID WP_042609483.1
Coordinates 2244549..2244842 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NF674_RS09975 Protein ID WP_042609482.1
Coordinates 2244238..2244546 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF674_RS09950 (NF674_09950) 2239374..2239997 + 624 WP_016774080.1 isochorismate family cysteine hydrolase YcaC -
NF674_RS09955 (NF674_09955) 2240209..2241636 - 1428 WP_227974176.1 mechanosensitive ion channel family protein -
NF674_RS09960 (NF674_09960) 2241745..2242767 - 1023 WP_227974177.1 alpha/beta hydrolase -
NF674_RS09965 (NF674_09965) 2242928..2243827 + 900 WP_024012435.1 LysR family transcriptional regulator -
NF674_RS09970 (NF674_09970) 2243899..2244165 - 267 WP_227974502.1 type II toxin-antitoxin system RelE/ParE family toxin -
NF674_RS09975 (NF674_09975) 2244238..2244546 - 309 WP_042609482.1 putative addiction module antidote protein Antitoxin
NF674_RS09980 (NF674_09980) 2244549..2244842 - 294 WP_042609483.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF674_RS09985 (NF674_09985) 2245070..2245762 - 693 WP_227974178.1 N-acetyltransferase -
NF674_RS09990 (NF674_09990) 2245759..2246949 - 1191 WP_227974179.1 GNAT family N-acetyltransferase -
NF674_RS09995 (NF674_09995) 2246954..2247643 - 690 WP_227974180.1 N-acetyltransferase -
NF674_RS10000 (NF674_10000) 2247705..2249624 - 1920 WP_252875919.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(25-89)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10662.26 Da        Isoelectric Point: 10.9839

>T249263 WP_042609483.1 NZ_CP099610:c2244842-2244549 [Pseudomonas moraviensis]
MTYLIQQTAIFHAWHRSIRDLRAKVAIARRIDRASTGNLGDAKSVGDGVSEMRLDVGAGYRVYFTIRNGAVIILLAGGDK
SSQSADIRRAQKMAKEV

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11086.63 Da        Isoelectric Point: 5.5656

>AT249263 WP_042609482.1 NZ_CP099610:c2244546-2244238 [Pseudomonas moraviensis]
MSQTLTNFDMVALLDSDEAISEYLSQVLADGDSEEFLRAIGYVLRARGMTQIAKNSGMGRESLYKAFAPGAKPRFDTVLK
VIHALGIDLYAQPGHVVNHAAT

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References