Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 4838388..4838893 Replicon chromosome
Accession NZ_CP099608
Organism Pseudomonas moraviensis strain OTU5BARRA1

Toxin (Protein)


Gene name relE Uniprot ID A0A2U1R9I4
Locus tag NF672_RS21355 Protein ID WP_042608353.1
Coordinates 4838639..4838893 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1N7ATY6
Locus tag NF672_RS21350 Protein ID WP_042608352.1
Coordinates 4838388..4838642 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF672_RS21325 (NF672_21325) 4834070..4834399 + 330 WP_042608348.1 hypothetical protein -
NF672_RS21330 (NF672_21330) 4834418..4834786 - 369 WP_039761415.1 PH domain-containing protein -
NF672_RS21335 (NF672_21335) 4834950..4835321 + 372 WP_065616631.1 hypothetical protein -
NF672_RS21340 (NF672_21340) 4835414..4836166 + 753 WP_064364320.1 hypothetical protein -
NF672_RS21345 (NF672_21345) 4836237..4838156 + 1920 WP_065616630.1 alkaline phosphatase D family protein -
NF672_RS21350 (NF672_21350) 4838388..4838642 + 255 WP_042608352.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NF672_RS21355 (NF672_21355) 4838639..4838893 + 255 WP_042608353.1 Txe/YoeB family addiction module toxin Toxin
NF672_RS21360 (NF672_21360) 4838887..4840074 - 1188 WP_042608354.1 aspartate aminotransferase family protein -
NF672_RS21365 (NF672_21365) 4840177..4841097 + 921 WP_042608355.1 LysR family transcriptional regulator -
NF672_RS21370 (NF672_21370) 4841137..4841541 + 405 WP_252873336.1 GNAT family N-acetyltransferase -
NF672_RS21375 (NF672_21375) 4841675..4842376 + 702 WP_064364315.1 hypothetical protein -
NF672_RS21380 (NF672_21380) 4842633..4843124 - 492 WP_016773306.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9967.53 Da        Isoelectric Point: 9.0627

>T249247 WP_042608353.1 NZ_CP099608:4838639-4838893 [Pseudomonas moraviensis]
MKIEFTPTGWEDYLWFQQNDKAGLKRINLLIKAIKREPFEGVGKPEALKHNMSGLWSRRVTAEHRLVYRVEDGEICVISC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9503.96 Da        Isoelectric Point: 7.0130

>AT249247 WP_042608352.1 NZ_CP099608:4838388-4838642 [Pseudomonas moraviensis]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLMKSIGELRAGKAKVRQ
LIEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U1R9I4

Antitoxin

Source ID Structure
AlphaFold DB A0A1N7ATY6

References