249245

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2743635..2744154 Replicon chromosome
Accession NZ_CP099608
Organism Pseudomonas moraviensis strain OTU5BARRA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF672_RS12075 Protein ID WP_252874460.1
Coordinates 2743873..2744154 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A423NSS0
Locus tag NF672_RS12070 Protein ID WP_042610420.1
Coordinates 2743635..2743883 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF672_RS12050 (NF672_12050) 2739258..2740268 + 1011 WP_252874458.1 AAA family ATPase -
NF672_RS12055 (NF672_12055) 2740184..2740933 + 750 WP_227974395.1 VWA domain-containing protein -
NF672_RS12060 (NF672_12060) 2741258..2742817 + 1560 WP_064361773.1 TerC family protein -
NF672_RS12065 (NF672_12065) 2742955..2743386 - 432 WP_252874459.1 thioredoxin family protein -
NF672_RS12070 (NF672_12070) 2743635..2743883 + 249 WP_042610420.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF672_RS12075 (NF672_12075) 2743873..2744154 + 282 WP_252874460.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF672_RS12080 (NF672_12080) 2744435..2745283 + 849 WP_064361771.1 transporter substrate-binding domain-containing protein -
NF672_RS12085 (NF672_12085) 2745335..2745997 + 663 WP_116658545.1 amino acid ABC transporter permease -
NF672_RS12090 (NF672_12090) 2746007..2746669 + 663 WP_042610356.1 amino acid ABC transporter permease -
NF672_RS12095 (NF672_12095) 2746666..2747457 + 792 WP_227974399.1 amino acid ABC transporter ATP-binding protein -
NF672_RS12100 (NF672_12100) 2747489..2747881 + 393 WP_252874461.1 RidA family protein -
NF672_RS12105 (NF672_12105) 2748090..2748854 + 765 WP_065617205.1 IclR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10833.64 Da        Isoelectric Point: 10.8161

>T249245 WP_252874460.1 NZ_CP099608:2743873-2744154 [Pseudomonas moraviensis]
MTYELEFSDKAWREWGKLGSELREQFKNKLLERLVNPHVPAARLKGLSNAYKIKLRSAGYRLVYRVRDEVLVVTVIAVGK
RQGGDVYRQALKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9057.46 Da        Isoelectric Point: 4.7768

>AT249245 WP_042610420.1 NZ_CP099608:2743635-2743883 [Pseudomonas moraviensis]
MTHIVLSHVVASISELKKNPMGTVAAGGGRSVAILNRNEPAFYCVPAKEYEAMMERLDDLELIALCRERENDPTIKVSID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A423NSS0

References