249244

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2246874..2247423 Replicon chromosome
Accession NZ_CP099608
Organism Pseudomonas moraviensis strain OTU5BARRA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF672_RS10020 Protein ID WP_083353138.1
Coordinates 2247148..2247423 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NF672_RS10015 Protein ID WP_083353139.1
Coordinates 2246874..2247146 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF672_RS09995 (NF672_09995) 2242254..2242877 + 624 WP_016774080.1 isochorismate family cysteine hydrolase YcaC -
NF672_RS10000 (NF672_10000) 2243089..2244516 - 1428 WP_252874280.1 mechanosensitive ion channel family protein -
NF672_RS10005 (NF672_10005) 2244625..2245647 - 1023 WP_252874281.1 alpha/beta hydrolase -
NF672_RS10010 (NF672_10010) 2245808..2246707 + 900 WP_024012435.1 LysR family transcriptional regulator -
NF672_RS10015 (NF672_10015) 2246874..2247146 + 273 WP_083353139.1 ribbon-helix-helix domain-containing protein Antitoxin
NF672_RS10020 (NF672_10020) 2247148..2247423 + 276 WP_083353138.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF672_RS10025 (NF672_10025) 2247523..2248320 + 798 WP_065615042.1 class I SAM-dependent methyltransferase -
NF672_RS10030 (NF672_10030) 2248458..2249150 - 693 WP_116657279.1 N-acetyltransferase -
NF672_RS10035 (NF672_10035) 2249220..2250011 - 792 WP_252874282.1 ChbG/HpnK family deacetylase -
NF672_RS10040 (NF672_10040) 2249983..2251170 - 1188 WP_252874283.1 GNAT family N-acetyltransferase -
NF672_RS10045 (NF672_10045) 2251175..2251864 - 690 WP_252874284.1 N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10701.38 Da        Isoelectric Point: 8.5043

>T249244 WP_083353138.1 NZ_CP099608:2247148-2247423 [Pseudomonas moraviensis]
MELKWTSKGLSDLTRLYEFLAAVNQPAAARTVQQLTAAPTMLLANPRLGERLEEFEPRDVRRILVGHYEMRYEIIGSTIY
LLRLWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10110.48 Da        Isoelectric Point: 5.6994

>AT249244 WP_083353139.1 NZ_CP099608:2246874-2247146 [Pseudomonas moraviensis]
MAATMKTRSVTAHVPVQLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQSVQAWADSL
TSDTPLKAPL

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References