249236

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 3112781..3113309 Replicon chromosome
Accession NZ_CP099602
Organism Pseudomonas siliginis strain OTU6MONTID1

Toxin (Protein)


Gene name parE Uniprot ID A0A554AHL9
Locus tag NF680_RS13945 Protein ID WP_041480302.1
Coordinates 3113019..3113309 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A341F4V9
Locus tag NF680_RS13940 Protein ID WP_016770738.1
Coordinates 3112781..3113026 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF680_RS13915 (NF680_13915) 3108414..3109709 + 1296 WP_252876351.1 OprD family porin -
NF680_RS13920 (NF680_13920) 3109936..3110589 + 654 WP_150635200.1 hypothetical protein -
NF680_RS13925 (NF680_13925) 3110586..3111101 + 516 WP_252867657.1 hypothetical protein -
NF680_RS13930 (NF680_13930) 3111110..3111619 + 510 WP_016774812.1 hypothetical protein -
NF680_RS13935 (NF680_13935) 3112080..3112439 + 360 WP_150635198.1 DUF6124 family protein -
NF680_RS13940 (NF680_13940) 3112781..3113026 + 246 WP_016770738.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NF680_RS13945 (NF680_13945) 3113019..3113309 + 291 WP_041480302.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF680_RS13955 (NF680_13955) 3113510..3115426 - 1917 Protein_2752 selenocysteine-specific translation elongation factor -
NF680_RS13960 (NF680_13960) 3115423..3116835 - 1413 WP_252876352.1 L-seryl-tRNA(Sec) selenium transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(8-78)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11136.67 Da        Isoelectric Point: 5.6837

>T249236 WP_041480302.1 NZ_CP099602:3113019-3113309 [Pseudomonas siliginis]
MAEYRLTPAAEADLEAIWTYTAQQWGLDQANRYIDILTESFEQLADRPKTAPACDAIRPGYRRCSVESHMIYFRITAYGI
AIIRILHDRMEAQRNL

Download         Length: 291 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9354.43 Da        Isoelectric Point: 7.3193

>AT249236 WP_016770738.1 NZ_CP099602:3112781-3113026 [Pseudomonas siliginis]
MATVRKTITVTDQQDHWIKAQIEAGHYTNDSEYIRDLIRREQERNAELETVRAALREGESSGAPRPFDADAFKKRMLRAH
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554AHL9

Antitoxin

Source ID Structure
AlphaFold DB A0A341F4V9

References