Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 474994..475625 Replicon chromosome
Accession NZ_CP099602
Organism Pseudomonas siliginis strain OTU6MONTID1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NF680_RS02080 Protein ID WP_252877298.1
Coordinates 475263..475625 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID J2YH56
Locus tag NF680_RS02075 Protein ID WP_008077592.1
Coordinates 474994..475263 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF680_RS02040 (NF680_02040) 470493..471038 - 546 WP_252877297.1 hypothetical protein -
NF680_RS02045 (NF680_02045) 471035..471289 - 255 WP_056787400.1 acyl carrier protein -
NF680_RS02050 (NF680_02050) 471299..471574 - 276 WP_095181011.1 phosphopantetheine-binding protein -
NF680_RS02055 (NF680_02055) 471552..472364 - 813 WP_041477597.1 lysophospholipid acyltransferase family protein -
NF680_RS02060 (NF680_02060) 472340..473065 - 726 WP_041477598.1 beta-ketoacyl synthase chain length factor -
NF680_RS02065 (NF680_02065) 473422..474192 + 771 WP_056787407.1 ParA family protein -
NF680_RS02070 (NF680_02070) 474323..474757 - 435 WP_095181008.1 thioredoxin TrxC -
NF680_RS02075 (NF680_02075) 474994..475263 + 270 WP_008077592.1 hypothetical protein Antitoxin
NF680_RS02080 (NF680_02080) 475263..475625 + 363 WP_252877298.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NF680_RS02085 (NF680_02085) 475631..477094 - 1464 WP_252877299.1 YdiU family protein -
NF680_RS02090 (NF680_02090) 477143..480496 - 3354 WP_252877300.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-115)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13400.33 Da        Isoelectric Point: 7.1665

>T249232 WP_252877298.1 NZ_CP099602:475263-475625 [Pseudomonas siliginis]
MVRRQPPQRGDVYWIDPNPVAGREMMNRHRFVVITPREINALGVSMTVPITSGGNFSRYMGLAVAITGHETNGVAVCNQV
RSFDIEQRVRDGTAKFIERLDDVTMSDIVDRVISAIDPLS

Download         Length: 363 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9521.94 Da        Isoelectric Point: 5.1069

>AT249232 WP_008077592.1 NZ_CP099602:474994-475263 [Pseudomonas siliginis]
MSVTSKIRRQGGAAVITIPPTLLKLLHLEVGAQLELNVVDGELIARPAVAATRKRYSLSELLEGAEELQKLNAQTSETLE
GDSVGRELG

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB J2YH56

References