Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 174068..174584 Replicon chromosome
Accession NZ_CP099602
Organism Pseudomonas siliginis strain OTU6MONTID1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF680_RS00735 Protein ID WP_252877214.1
Coordinates 174303..174584 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2U1R4X8
Locus tag NF680_RS00730 Protein ID WP_041477418.1
Coordinates 174068..174313 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF680_RS00710 (NF680_00710) 169429..170967 + 1539 WP_252877212.1 MFS transporter -
NF680_RS00715 (NF680_00715) 170995..172062 + 1068 WP_150637840.1 HlyD family secretion protein -
NF680_RS00720 (NF680_00720) 172059..173654 + 1596 WP_252877213.1 efflux transporter outer membrane subunit -
NF680_RS00725 (NF680_00725) 173733..173978 + 246 WP_252868578.1 DUF2789 domain-containing protein -
NF680_RS00730 (NF680_00730) 174068..174313 + 246 WP_041477418.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF680_RS00735 (NF680_00735) 174303..174584 + 282 WP_252877214.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF680_RS00740 (NF680_00740) 174948..175376 + 429 WP_016772266.1 winged helix DNA-binding protein -
NF680_RS00745 (NF680_00745) 175373..177436 + 2064 WP_150637842.1 FUSC family protein -
NF680_RS00750 (NF680_00750) 177433..177642 + 210 WP_016772264.1 DUF1656 domain-containing protein -
NF680_RS00755 (NF680_00755) 177639..178526 + 888 WP_252877215.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10812.70 Da        Isoelectric Point: 10.5812

>T249230 WP_252877214.1 NZ_CP099602:174303-174584 [Pseudomonas siliginis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHGMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERSSVYDAARNR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8806.13 Da        Isoelectric Point: 4.4988

>AT249230 WP_041477418.1 NZ_CP099602:174068-174313 [Pseudomonas siliginis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2U1R4X8

References