Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 3085962..3086490 Replicon chromosome
Accession NZ_CP099601
Organism Pseudomonas siliginis strain OTU6MONEA1

Toxin (Protein)


Gene name parE Uniprot ID A0A554AHL9
Locus tag NF679_RS13785 Protein ID WP_041480302.1
Coordinates 3086200..3086490 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A341F4V9
Locus tag NF679_RS13780 Protein ID WP_016770738.1
Coordinates 3085962..3086207 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF679_RS13755 (NF679_13755) 3081580..3082890 + 1311 WP_252867656.1 OprD family porin -
NF679_RS13760 (NF679_13760) 3083117..3083770 + 654 WP_150635200.1 hypothetical protein -
NF679_RS13765 (NF679_13765) 3083767..3084282 + 516 WP_252867657.1 hypothetical protein -
NF679_RS13770 (NF679_13770) 3084291..3084800 + 510 WP_016774812.1 hypothetical protein -
NF679_RS13775 (NF679_13775) 3085261..3085620 + 360 WP_150635198.1 DUF6124 family protein -
NF679_RS13780 (NF679_13780) 3085962..3086207 + 246 WP_016770738.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NF679_RS13785 (NF679_13785) 3086200..3086490 + 291 WP_041480302.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF679_RS13795 (NF679_13795) 3086691..3088607 - 1917 WP_252869552.1 selenocysteine-specific translation elongation factor -
NF679_RS13800 (NF679_13800) 3088604..3090016 - 1413 WP_252867658.1 L-seryl-tRNA(Sec) selenium transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(8-78)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11136.67 Da        Isoelectric Point: 5.6837

>T249227 WP_041480302.1 NZ_CP099601:3086200-3086490 [Pseudomonas siliginis]
MAEYRLTPAAEADLEAIWTYTAQQWGLDQANRYIDILTESFEQLADRPKTAPACDAIRPGYRRCSVESHMIYFRITAYGI
AIIRILHDRMEAQRNL

Download         Length: 291 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9354.43 Da        Isoelectric Point: 7.3193

>AT249227 WP_016770738.1 NZ_CP099601:3085962-3086207 [Pseudomonas siliginis]
MATVRKTITVTDQQDHWIKAQIEAGHYTNDSEYIRDLIRREQERNAELETVRAALREGESSGAPRPFDADAFKKRMLRAH
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554AHL9

Antitoxin

Source ID Structure
AlphaFold DB A0A341F4V9

References