Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 470439..471070 Replicon chromosome
Accession NZ_CP099601
Organism Pseudomonas siliginis strain OTU6MONEA1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NF679_RS02080 Protein ID WP_252868668.1
Coordinates 470708..471070 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID J2YH56
Locus tag NF679_RS02075 Protein ID WP_008077592.1
Coordinates 470439..470708 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF679_RS02040 (NF679_02040) 465936..466481 - 546 WP_252868667.1 hypothetical protein -
NF679_RS02045 (NF679_02045) 466478..466732 - 255 WP_056787400.1 acyl carrier protein -
NF679_RS02050 (NF679_02050) 466742..467017 - 276 WP_095181011.1 phosphopantetheine-binding protein -
NF679_RS02055 (NF679_02055) 466995..467807 - 813 WP_041477597.1 lysophospholipid acyltransferase family protein -
NF679_RS02060 (NF679_02060) 467783..468508 - 726 WP_041477598.1 beta-ketoacyl synthase chain length factor -
NF679_RS02065 (NF679_02065) 468865..469635 + 771 WP_056787407.1 ParA family protein -
NF679_RS02070 (NF679_02070) 469768..470202 - 435 WP_095181008.1 thioredoxin TrxC -
NF679_RS02075 (NF679_02075) 470439..470708 + 270 WP_008077592.1 hypothetical protein Antitoxin
NF679_RS02080 (NF679_02080) 470708..471070 + 363 WP_252868668.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NF679_RS02085 (NF679_02085) 471076..472539 - 1464 WP_252868669.1 YdiU family protein -
NF679_RS02090 (NF679_02090) 472588..475941 - 3354 WP_252868670.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-115)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13434.40 Da        Isoelectric Point: 8.0357

>T249223 WP_252868668.1 NZ_CP099601:470708-471070 [Pseudomonas siliginis]
MVRRQPPQRGDVYWIDPNPVAGREMMNRHRFVVITPREINALGVSMTVPVTSGGNFSRYMGLAVAITGHETNGVAVCNQV
RSFDIEQRVRYGTAKFIERLDDVTMSDIVDRVISAIDPLS

Download         Length: 363 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9521.94 Da        Isoelectric Point: 5.1069

>AT249223 WP_008077592.1 NZ_CP099601:470439-470708 [Pseudomonas siliginis]
MSVTSKIRRQGGAAVITIPPTLLKLLHLEVGAQLELNVVDGELIARPAVAATRKRYSLSELLEGAEELQKLNAQTSETLE
GDSVGRELG

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB J2YH56

References