Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 173927..174443 Replicon chromosome
Accession NZ_CP099601
Organism Pseudomonas siliginis strain OTU6MONEA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF679_RS00740 Protein ID WP_071174010.1
Coordinates 174162..174443 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2U1R4X8
Locus tag NF679_RS00735 Protein ID WP_041477418.1
Coordinates 173927..174172 (+) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF679_RS00715 (NF679_00715) 169288..170826 + 1539 WP_252868576.1 MFS transporter -
NF679_RS00720 (NF679_00720) 170854..171921 + 1068 WP_150637840.1 HlyD family secretion protein -
NF679_RS00725 (NF679_00725) 171918..173513 + 1596 WP_252868577.1 efflux transporter outer membrane subunit -
NF679_RS00730 (NF679_00730) 173592..173837 + 246 WP_252868578.1 DUF2789 domain-containing protein -
NF679_RS00735 (NF679_00735) 173927..174172 + 246 WP_041477418.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF679_RS00740 (NF679_00740) 174162..174443 + 282 WP_071174010.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF679_RS00745 (NF679_00745) 174805..175233 + 429 WP_016772266.1 winged helix DNA-binding protein -
NF679_RS00750 (NF679_00750) 175230..177293 + 2064 WP_252868579.1 FUSC family protein -
NF679_RS00755 (NF679_00755) 177290..177499 + 210 WP_016772264.1 DUF1656 domain-containing protein -
NF679_RS00760 (NF679_00760) 177496..178383 + 888 WP_252868580.1 HlyD family secretion protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10842.73 Da        Isoelectric Point: 10.5812

>T249221 WP_071174010.1 NZ_CP099601:174162-174443 [Pseudomonas siliginis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHSMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERSSVYDAARNR

Download         Length: 282 bp


Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8806.13 Da        Isoelectric Point: 4.4988

>AT249221 WP_041477418.1 NZ_CP099601:173927-174172 [Pseudomonas siliginis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Download         Length: 246 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A2U1R4X8

References