249216

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 902702..903291 Replicon chromosome
Accession NZ_CP099600
Organism Pseudomonas siliginis strain OTU6MEDAA1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NF678_RS03780 Protein ID WP_056782877.1
Coordinates 903040..903291 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NF678_RS03775 Protein ID WP_056782875.1
Coordinates 902702..903043 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF678_RS03750 (NF678_03750) 898374..898775 + 402 WP_016771753.1 30S ribosome-binding factor RbfA -
NF678_RS03755 (NF678_03755) 898780..899697 + 918 WP_024011571.1 tRNA pseudouridine(55) synthase TruB -
NF678_RS03760 (NF678_03760) 899840..900109 + 270 WP_016771751.1 30S ribosomal protein S15 -
NF678_RS03765 (NF678_03765) 900314..902419 + 2106 WP_024011572.1 polyribonucleotide nucleotidyltransferase -
NF678_RS03775 (NF678_03775) 902702..903043 - 342 WP_056782875.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NF678_RS03780 (NF678_03780) 903040..903291 - 252 WP_056782877.1 type II toxin-antitoxin system HicA family toxin Toxin
NF678_RS03785 (NF678_03785) 903646..903945 + 300 WP_076565788.1 DUF6388 family protein -
NF678_RS03790 (NF678_03790) 904026..904874 - 849 WP_076565789.1 carboxylating nicotinate-nucleotide diphosphorylase -
NF678_RS03795 (NF678_03795) 905142..907319 + 2178 WP_252883167.1 DUF1631 domain-containing protein -
NF678_RS03800 (NF678_03800) 907384..907944 + 561 WP_122747368.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-76)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9164.60 Da        Isoelectric Point: 10.5416

>T249216 WP_056782877.1 NZ_CP099600:c903291-903040 [Pseudomonas siliginis]
MSKTEKLLAKLVNGQSAFTWSELVTLLARLGYSQLEGSGSRIKFDNGNPSAMINLHKPHPGNEIKTYARRQIIEQLKTGG
LIP

Download         Length: 252 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12593.23 Da        Isoelectric Point: 6.3189

>AT249216 WP_056782875.1 NZ_CP099600:c903043-902702 [Pseudomonas siliginis]
MSSQLHYKGYVGSIEASTEDKCLFGKLLFIRALVNYEGQTVAELEAAFREAVDDYLQTCQQLGQKPEIPCKGSFNVRIGH
DLHLAAALAATRQNVSLNDLTRQALNEYLQHHA

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References