Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 176591..177107 Replicon chromosome
Accession NZ_CP099600
Organism Pseudomonas siliginis strain OTU6MEDAA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF678_RS00730 Protein ID WP_252882968.1
Coordinates 176826..177107 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2U1R4X8
Locus tag NF678_RS00725 Protein ID WP_041477418.1
Coordinates 176591..176836 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF678_RS00705 (NF678_00705) 171952..173490 + 1539 WP_252882966.1 MFS transporter -
NF678_RS00710 (NF678_00710) 173518..174585 + 1068 WP_150637840.1 HlyD family secretion protein -
NF678_RS00715 (NF678_00715) 174582..176177 + 1596 WP_252882967.1 efflux transporter outer membrane subunit -
NF678_RS00720 (NF678_00720) 176256..176501 + 246 WP_150742984.1 DUF2789 domain-containing protein -
NF678_RS00725 (NF678_00725) 176591..176836 + 246 WP_041477418.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF678_RS00730 (NF678_00730) 176826..177107 + 282 WP_252882968.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF678_RS00735 (NF678_00735) 177471..177899 + 429 WP_016772266.1 winged helix DNA-binding protein -
NF678_RS00740 (NF678_00740) 177896..179959 + 2064 WP_150742985.1 FUSC family protein -
NF678_RS00745 (NF678_00745) 179956..180165 + 210 WP_016772264.1 DUF1656 domain-containing protein -
NF678_RS00750 (NF678_00750) 180162..181049 + 888 WP_056786955.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10839.73 Da        Isoelectric Point: 10.5812

>T249215 WP_252882968.1 NZ_CP099600:176826-177107 [Pseudomonas siliginis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHGMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERNSVYDAARNR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8806.13 Da        Isoelectric Point: 4.4988

>AT249215 WP_041477418.1 NZ_CP099600:176591-176836 [Pseudomonas siliginis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2U1R4X8

References