Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 174713..175229 Replicon chromosome
Accession NZ_CP099599
Organism Pseudomonas siliginis strain OTU6ESPEB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF677_RS00730 Protein ID WP_252877214.1
Coordinates 174948..175229 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2U1R4X8
Locus tag NF677_RS00725 Protein ID WP_041477418.1
Coordinates 174713..174958 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF677_RS00705 (NF677_00705) 170074..171612 + 1539 WP_252885114.1 MFS transporter -
NF677_RS00710 (NF677_00710) 171640..172707 + 1068 WP_150637840.1 HlyD family secretion protein -
NF677_RS00715 (NF677_00715) 172704..174299 + 1596 WP_252885115.1 efflux transporter outer membrane subunit -
NF677_RS00720 (NF677_00720) 174378..174623 + 246 WP_252885116.1 DUF2789 domain-containing protein -
NF677_RS00725 (NF677_00725) 174713..174958 + 246 WP_041477418.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF677_RS00730 (NF677_00730) 174948..175229 + 282 WP_252877214.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF677_RS00735 (NF677_00735) 175591..176019 + 429 WP_150743122.1 winged helix DNA-binding protein -
NF677_RS00740 (NF677_00740) 176016..178079 + 2064 WP_150742985.1 FUSC family protein -
NF677_RS00745 (NF677_00745) 178076..178285 + 210 WP_016772264.1 DUF1656 domain-containing protein -
NF677_RS00750 (NF677_00750) 178282..179169 + 888 WP_016772263.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10812.70 Da        Isoelectric Point: 10.5812

>T249208 WP_252877214.1 NZ_CP099599:174948-175229 [Pseudomonas siliginis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHGMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERSSVYDAARNR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8806.13 Da        Isoelectric Point: 4.4988

>AT249208 WP_041477418.1 NZ_CP099599:174713-174958 [Pseudomonas siliginis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2U1R4X8

References