249204

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2254690..2255140 Replicon chromosome
Accession NZ_CP099598
Organism Pseudomonas siliginis strain OTU6BANIB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF676_RS10545 Protein ID WP_082228561.1
Coordinates 2254690..2254959 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NF676_RS10550 Protein ID WP_056786779.1
Coordinates 2254949..2255140 (-) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF676_RS10525 (NF676_10525) 2250151..2250774 + 624 WP_016774080.1 isochorismate family cysteine hydrolase YcaC -
NF676_RS10530 (NF676_10530) 2250999..2252426 - 1428 WP_252887663.1 mechanosensitive ion channel family protein -
NF676_RS10535 (NF676_10535) 2252535..2253557 - 1023 WP_252887664.1 alpha/beta hydrolase -
NF676_RS10540 (NF676_10540) 2253718..2254617 + 900 WP_041478583.1 LysR family transcriptional regulator -
NF676_RS10545 (NF676_10545) 2254690..2254959 - 270 WP_082228561.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
NF676_RS10550 (NF676_10550) 2254949..2255140 - 192 WP_056786779.1 hypothetical protein Antitoxin
NF676_RS10555 (NF676_10555) 2255449..2256246 + 798 WP_252887665.1 class I SAM-dependent methyltransferase -
NF676_RS10560 (NF676_10560) 2256373..2257065 - 693 WP_041478587.1 N-acetyltransferase -
NF676_RS10565 (NF676_10565) 2257123..2257914 - 792 WP_041478588.1 ChbG/HpnK family deacetylase -
NF676_RS10570 (NF676_10570) 2257886..2259073 - 1188 WP_252887666.1 GNAT family N-acetyltransferase -
NF676_RS10575 (NF676_10575) 2259078..2259767 - 690 WP_095179528.1 N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10263.67 Da        Isoelectric Point: 7.3990

>T249204 WP_082228561.1 NZ_CP099598:c2254959-2254690 [Pseudomonas siliginis]
MQIEWRPEAKADLSNILRYIGERNFAAAVSLSKSIEESTTSLSVHPHLYRKGRSPGTREIVVHPNYVVIYEVTDRIEILS
VLHTRQEYP

Download         Length: 270 bp

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7158.95 Da        Isoelectric Point: 5.4992

>AT249204 WP_056786779.1 NZ_CP099598:c2255140-2254949 [Pseudomonas siliginis]
MDGKIFPDDSGFKNNEQAASHDRWLRAKVQASRDDPHPSLPHEDVMADMHALIESMRKKVDAD

Download         Length: 192 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References