Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 511313..511944 Replicon chromosome
Accession NZ_CP099598
Organism Pseudomonas siliginis strain OTU6BANIB1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NF676_RS02885 Protein ID WP_056787412.1
Coordinates 511582..511944 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID J2YH56
Locus tag NF676_RS02880 Protein ID WP_008077592.1
Coordinates 511313..511582 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF676_RS02845 (NF676_02845) 506812..507357 - 546 WP_041477595.1 membrane protein -
NF676_RS02850 (NF676_02850) 507354..507608 - 255 WP_016772026.1 acyl carrier protein -
NF676_RS02855 (NF676_02855) 507618..507893 - 276 WP_039756723.1 phosphopantetheine-binding protein -
NF676_RS02860 (NF676_02860) 507871..508683 - 813 WP_041477597.1 lysophospholipid acyltransferase family protein -
NF676_RS02865 (NF676_02865) 508659..509384 - 726 WP_041477598.1 beta-ketoacyl synthase chain length factor -
NF676_RS02870 (NF676_02870) 509741..510511 + 771 WP_056787407.1 ParA family protein -
NF676_RS02875 (NF676_02875) 510642..511076 - 435 WP_056787410.1 thioredoxin TrxC -
NF676_RS02880 (NF676_02880) 511313..511582 + 270 WP_008077592.1 hypothetical protein Antitoxin
NF676_RS02885 (NF676_02885) 511582..511944 + 363 WP_056787412.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NF676_RS02890 (NF676_02890) 511950..513413 - 1464 WP_252887201.1 YdiU family protein -
NF676_RS02895 (NF676_02895) 513462..516815 - 3354 WP_252887202.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-115)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13386.31 Da        Isoelectric Point: 7.1665

>T249202 WP_056787412.1 NZ_CP099598:511582-511944 [Pseudomonas siliginis]
MVRRQPPQRGDVYWIDPNPVAGREMMNRHRFVVITPREINALGVSMTVPVTSGGNFSRYMGLAVAITGHETNGVAVCNQV
RSFDIEQRVRDGTAKFIERLDDVTMSDIVDRVISAIDPLS

Download         Length: 363 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9521.94 Da        Isoelectric Point: 5.1069

>AT249202 WP_008077592.1 NZ_CP099598:511313-511582 [Pseudomonas siliginis]
MSVTSKIRRQGGAAVITIPPTLLKLLHLEVGAQLELNVVDGELIARPAVAATRKRYSLSELLEGAEELQKLNAQTSETLE
GDSVGRELG

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB J2YH56

References