Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 174285..174801 Replicon chromosome
Accession NZ_CP099598
Organism Pseudomonas siliginis strain OTU6BANIB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF676_RS01320 Protein ID WP_071174010.1
Coordinates 174520..174801 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2U1R4X8
Locus tag NF676_RS01315 Protein ID WP_041477418.1
Coordinates 174285..174530 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF676_RS01295 (NF676_01295) 169646..171184 + 1539 WP_252887098.1 MFS transporter -
NF676_RS01300 (NF676_01300) 171212..172279 + 1068 WP_252887099.1 HlyD family secretion protein -
NF676_RS01305 (NF676_01305) 172276..173871 + 1596 WP_252887100.1 efflux transporter outer membrane subunit -
NF676_RS01310 (NF676_01310) 173950..174195 + 246 WP_252887101.1 DUF2789 domain-containing protein -
NF676_RS01315 (NF676_01315) 174285..174530 + 246 WP_041477418.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF676_RS01320 (NF676_01320) 174520..174801 + 282 WP_071174010.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF676_RS01325 (NF676_01325) 175165..175593 + 429 WP_016772266.1 winged helix DNA-binding protein -
NF676_RS01330 (NF676_01330) 175590..177653 + 2064 WP_252887102.1 FUSC family protein -
NF676_RS01335 (NF676_01335) 177650..177859 + 210 WP_016772264.1 DUF1656 domain-containing protein -
NF676_RS01340 (NF676_01340) 177856..178743 + 888 WP_056786955.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10842.73 Da        Isoelectric Point: 10.5812

>T249200 WP_071174010.1 NZ_CP099598:174520-174801 [Pseudomonas siliginis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHSMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERSSVYDAARNR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8806.13 Da        Isoelectric Point: 4.4988

>AT249200 WP_041477418.1 NZ_CP099598:174285-174530 [Pseudomonas siliginis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2U1R4X8

References