249194

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 905513..906102 Replicon chromosome
Accession NZ_CP099596
Organism Pseudomonas siliginis strain OTU6BAGNBB1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NF675_RS03800 Protein ID WP_252879420.1
Coordinates 905851..906102 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NF675_RS03795 Protein ID WP_056782875.1
Coordinates 905513..905854 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF675_RS03770 (NF675_03770) 901184..901585 + 402 WP_016771753.1 30S ribosome-binding factor RbfA -
NF675_RS03775 (NF675_03775) 901590..902507 + 918 WP_024011571.1 tRNA pseudouridine(55) synthase TruB -
NF675_RS03780 (NF675_03780) 902651..902920 + 270 WP_016771751.1 30S ribosomal protein S15 -
NF675_RS03785 (NF675_03785) 903125..905230 + 2106 WP_024011572.1 polyribonucleotide nucleotidyltransferase -
NF675_RS03795 (NF675_03795) 905513..905854 - 342 WP_056782875.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NF675_RS03800 (NF675_03800) 905851..906102 - 252 WP_252879420.1 type II toxin-antitoxin system HicA family toxin Toxin
NF675_RS03805 (NF675_03805) 906457..906756 + 300 WP_076565788.1 DUF6388 family protein -
NF675_RS03810 (NF675_03810) 906844..907692 - 849 WP_076565789.1 carboxylating nicotinate-nucleotide diphosphorylase -
NF675_RS03815 (NF675_03815) 907960..910137 + 2178 WP_252879421.1 DUF1631 domain-containing protein -
NF675_RS03820 (NF675_03820) 910202..910762 + 561 WP_122747368.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-76)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9198.62 Da        Isoelectric Point: 10.5416

>T249194 WP_252879420.1 NZ_CP099596:c906102-905851 [Pseudomonas siliginis]
MSKTEKLLAKLVNGQSAFTWSEFVTLLARLGYSQLEGSGSRIKFDNGNPSAMINLHKPHPGNEIKTYARRQIIEQLKTGG
LIP

Download         Length: 252 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12593.23 Da        Isoelectric Point: 6.3189

>AT249194 WP_056782875.1 NZ_CP099596:c905854-905513 [Pseudomonas siliginis]
MSSQLHYKGYVGSIEASTEDKCLFGKLLFIRALVNYEGQTVAELEAAFREAVDDYLQTCQQLGQKPEIPCKGSFNVRIGH
DLHLAAALAATRQNVSLNDLTRQALNEYLQHHA

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References