249193

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 177789..178305 Replicon chromosome
Accession NZ_CP099596
Organism Pseudomonas siliginis strain OTU6BAGNBB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NF675_RS00730 Protein ID WP_071174010.1
Coordinates 178024..178305 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2U1R4X8
Locus tag NF675_RS00725 Protein ID WP_041477418.1
Coordinates 177789..178034 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF675_RS00705 (NF675_00705) 173150..174688 + 1539 WP_252879203.1 MFS transporter -
NF675_RS00710 (NF675_00710) 174716..175783 + 1068 WP_252879204.1 HlyD family secretion protein -
NF675_RS00715 (NF675_00715) 175924..177375 + 1452 WP_252880128.1 efflux transporter outer membrane subunit -
NF675_RS00720 (NF675_00720) 177454..177699 + 246 WP_252879205.1 DUF2789 domain-containing protein -
NF675_RS00725 (NF675_00725) 177789..178034 + 246 WP_041477418.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NF675_RS00730 (NF675_00730) 178024..178305 + 282 WP_071174010.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NF675_RS00735 (NF675_00735) 178669..179097 + 429 WP_150743122.1 winged helix DNA-binding protein -
NF675_RS00740 (NF675_00740) 179094..181157 + 2064 WP_150742985.1 FUSC family protein -
NF675_RS00745 (NF675_00745) 181154..181363 + 210 WP_016772264.1 DUF1656 domain-containing protein -
NF675_RS00750 (NF675_00750) 181360..182247 + 888 WP_056786955.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10842.73 Da        Isoelectric Point: 10.5812

>T249193 WP_071174010.1 NZ_CP099596:178024-178305 [Pseudomonas siliginis]
MTYKLEFLPSAHKEWNKLGHTLREQFKKKLGERLKLPRIPADALHSMPDCYKIKLKASGYRLVYQVIDERVVVSVLAVGK
RERSSVYDAARNR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8806.13 Da        Isoelectric Point: 4.4988

>AT249193 WP_041477418.1 NZ_CP099596:177789-178034 [Pseudomonas siliginis]
MQSVLADMAVSVSELKKNPTAVLNGAHGGAVAVLNHNRVMGYMVPAEVYEAMMERLDDLELADIVRSRLHETPISVSLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2U1R4X8

References