Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
Location | 480337..480974 | Replicon | chromosome |
Accession | NC_014551 | ||
Organism | Bacillus amyloliquefaciens DSM 7 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | G4NU33 |
Locus tag | BAMF_RS22640 | Protein ID | WP_003156187.1 |
Coordinates | 480624..480974 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | I2HMS5 |
Locus tag | BAMF_RS22635 | Protein ID | WP_003156188.1 |
Coordinates | 480337..480618 (+) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BAMF_RS22615 | 476703..477302 | - | 600 | WP_013351092.1 | rhomboid family intramembrane serine protease | - |
BAMF_RS22620 | 477395..477760 | + | 366 | WP_013351093.1 | holo-ACP synthase | - |
BAMF_RS22625 | 477925..478932 | + | 1008 | WP_013351094.1 | outer membrane lipoprotein carrier protein LolA | - |
BAMF_RS22630 | 479049..480218 | + | 1170 | WP_013351095.1 | alanine racemase | - |
BAMF_RS22635 | 480337..480618 | + | 282 | WP_003156188.1 | type II toxin-antitoxin system antitoxin EndoAI | Antitoxin |
BAMF_RS22640 | 480624..480974 | + | 351 | WP_003156187.1 | type II toxin-antitoxin system endoribonuclease NdoA | Toxin |
BAMF_RS22645 | 481095..481916 | + | 822 | WP_013351096.1 | STAS domain-containing protein | - |
BAMF_RS22650 | 481921..482286 | + | 366 | WP_003156180.1 | RsbT antagonist protein RsbS | - |
BAMF_RS22655 | 482289..482690 | + | 402 | WP_013351097.1 | anti-sigma regulatory factor | - |
BAMF_RS22660 | 482702..483709 | + | 1008 | WP_013351098.1 | PP2C family protein-serine/threonine phosphatase | - |
BAMF_RS22665 | 483773..484102 | + | 330 | WP_013351099.1 | anti-sigma factor antagonist | - |
BAMF_RS22670 | 484099..484581 | + | 483 | WP_013351100.1 | anti-sigma B factor RsbW | - |
BAMF_RS22675 | 484547..485335 | + | 789 | WP_013351101.1 | RNA polymerase sigma factor SigB | - |
BAMF_RS22680 | 485335..485937 | + | 603 | WP_013351102.1 | SpoIIE family protein phosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12977.98 Da Isoelectric Point: 4.8781
>T24917 WP_003156187.1 NC_014551:480624-480974 [Bacillus amyloliquefaciens DSM 7 = ATCC 23350]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
Download Length: 351 bp
>T24917 NC_014551:480624-480974 [Bacillus amyloliquefaciens DSM 7 = ATCC 23350]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG
Antitoxin
Download Length: 94 a.a. Molecular weight: 10562.92 Da Isoelectric Point: 6.4706
>AT24917 WP_003156188.1 NC_014551:480337-480618 [Bacillus amyloliquefaciens DSM 7 = ATCC 23350]
MSESSARTEMKISLPENLVAELDGVAMREKRSRNELISQAVRAYVSERTTRHNRDLMRRGYMEMAKINLNISSEAHYAEC
EAETTVERLVSGG
MSESSARTEMKISLPENLVAELDGVAMREKRSRNELISQAVRAYVSERTTRHNRDLMRRGYMEMAKINLNISSEAHYAEC
EAETTVERLVSGG
Download Length: 282 bp
>AT24917 NC_014551:480337-480618 [Bacillus amyloliquefaciens DSM 7 = ATCC 23350]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCTGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAGGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATTTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACGGTTGAGCGCTTAGTCAGCGGAGGATAA
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCTGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAGGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATTTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACGGTTGAGCGCTTAGTCAGCGGAGGATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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