Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1945582..1945853 Replicon chromosome
Accession NZ_CP099588
Organism Escherichia coli strain EMG2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1945712..1945815 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1945582..1945853 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NHF38_RS09290 1942137..1942799 - 663 WP_000944256.1 exodeoxyribonuclease X -
NHF38_RS09295 1942823..1943479 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NHF38_RS09300 1943581..1943811 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NHF38_RS09305 1943950..1944324 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NHF38_RS09310 1944328..1945200 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
NHF38_RS09315 1945213..1945554 + 342 WP_000976476.1 YebY family protein -
- 1945582..1945853 - 272 - - Antitoxin
- 1945712..1945815 + 104 - - Toxin
NHF38_RS09320 1945950..1946606 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NHF38_RS09325 1946607..1946798 - 192 WP_000457842.1 YebW family protein -
NHF38_RS09330 1946903..1947139 - 237 WP_001295499.1 YebV family protein -
NHF38_RS09335 1947257..1948696 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T249141 NZ_CP099588:1945712-1945815 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT249141 NZ_CP099588:c1945853-1945582 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References