Detailed information of TA system TA024912

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1373202..1373697
• Replicon: chromosome
• Accession: NC_014506
• Organism: Sulfurimonas autotrophica DSM 16294

Toxin (Protein)

• Gene name: -
• Uniprot ID: E0UTZ4
• Locus tag: SAUT_RS07030
• Protein ID: WP_013327191.1
• Coordinates: 1373202..1373462 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: E0UTZ5
• Locus tag: SAUT_RS07035
• Protein ID: WP_013327192.1
• Coordinates: 1373452..1373697 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAUT_RS07005	1368472..1369362	+	891	WP_013327186.1	efflux RND transporter periplasmic adaptor subunit	-
SAUT_RS07010	1369363..1370556	+	1194	WP_013327187.1	ABC transporter permease	-
SAUT_RS07015	1370573..1371055	-	483	WP_013327188.1	hypothetical protein	-
SAUT_RS07020	1371156..1372034	+	879	WP_013327189.1	DUF808 domain-containing protein	-
SAUT_RS07025	1372178..1373074	+	897	WP_013327190.1	GIY-YIG nuclease family protein	-
SAUT_RS07030	1373202..1373462	+	261	WP_013327191.1	BrnT family toxin	Toxin
SAUT_RS07035	1373452..1373697	+	246	WP_013327192.1	CopG family transcriptional regulator	Antitoxin
SAUT_RS07040	1373734..1374639	+	906	WP_013327193.1	phosphate-starvation-inducible PsiE family protein	-
SAUT_RS07045	1374690..1376645	+	1956	WP_013327194.1	ABC-F family ATP-binding cassette domain-containing protein	-
SAUT_RS07050	1376648..1377145	+	498	WP_013327195.1	preQ(1) synthase	-
SAUT_RS07055	1377145..1377504	+	360	WP_013327196.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

• CopG antitoxin (14-70)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10500.89 Da
• Isoelectric Point: 5.9205

>T24912 WP_013327191.1 NC_014506:1373202-1373462 [Sulfurimonas autotrophica DSM 16294]
MKYEYDENKSLLNKQKHGIDFEDAKLLWNDDRMVEIETSYEDEIRFINIGKIGTRFYTIVTTYRKDKIRIISARRSREKE
IEIYES

Nucleotide

• Length: 261 bp

>T24912 NC_014506:1373202-1373462 [Sulfurimonas autotrophica DSM 16294]
ATGAAATACGAATATGATGAAAATAAAAGCTTATTAAATAAGCAAAAACATGGCATAGATTTTGAAGACGCTAAGCTTCT
TTGGAATGATGACAGAATGGTTGAAATCGAAACATCATATGAAGATGAAATTCGTTTTATTAATATTGGAAAAATTGGAA
CTAGATTTTATACTATAGTTACAACTTACCGTAAAGATAAAATTAGAATTATTTCTGCAAGAAGATCACGAGAAAAGGAG
ATTGAAATTTATGAAAGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9662.16 Da
• Isoelectric Point: 4.9150

>AT24912 WP_013327192.1 NC_014506:1373452-1373697 [Sulfurimonas autotrophica DSM 16294]
MKAEEFDKIFDDNEEDIIEYLDLSKIKRPNLEPKRINIDFPTWMVKKLDEEAQHIGVSRQAIIKTWLADKIMELEHHKLA
V

Nucleotide

• Length: 246 bp

>AT24912 NC_014506:1373452-1373697 [Sulfurimonas autotrophica DSM 16294]
ATGAAAGCTGAAGAATTTGATAAAATTTTTGATGATAATGAAGAAGATATAATTGAATATCTTGATTTATCAAAAATAAA
AAGACCTAACCTTGAACCAAAAAGAATCAATATTGATTTTCCTACTTGGATGGTGAAAAAACTAGATGAAGAAGCACAGC
ATATCGGTGTAAGCCGTCAAGCAATTATAAAAACATGGCTAGCTGATAAAATTATGGAACTGGAACATCACAAACTAGCT
GTATAA

Structures

Toxin

• AlphaFold DB: E0UTZ4

Antitoxin

• AlphaFold DB: E0UTZ5